Functional ROMPgel

ROMPgels and Other Functional Metathesis-based Polymers... 

Many 5-aryl-l,3-oxazoles, bearing various functions at the aryl group, can be prepared in good yields of 68-90% and with high purities from aldehydes and ROMPgel TosMIC reagent 1612 they are purified only by filtration without any need for chromatography [1203]. This makes the method particularly well-suited for use in combinatorial chemistry. 

Later, Barrett created the term ROMPgel for linear polymers, which swell but do not dissolve in certain solvents because of solubility restrictions governed by the nature of the functional monomer used. Such ROMPgels were prepared with a variety of different functional groups including phosphines [3], allyl-boronates [25], a polymeric Tosmic reagent [26], naphthalenes, and biphenyls [27], alkylphosphonates [28], as well as anhydrides [29], some in a precipitation polymerization setup similar to the one described by our group. 

Scheme 17 Preparation of ROMPGELs and functional monomers used.

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