Functional models used to study dopamine receptor ligands

7 Functional models used to study dopamine receptor ligands 

There are a large number of generally accepted in vitro and in vivo test models available for the evaluation of centrally acting dopamine receptor agonists and antagonists. These models give information about the effect on pre- and postsynaptic dopamine receptors. The models for postsynaptic receptors can also be used to determine the involvement of different receptor subtypes on the effect. In this part only the in vivo models used in this thesis are discussed briefly. 

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