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Functional implications of sprouting

The implications of sprouting of the dopamine neurons as models for the repair of the nervous system are evident. Similarly, the importance of an understanding of the factors that contribute to and regulate the phenotype of repairing neurons is also clear. This information will be essential in understanding how neurons may participate in both plasticity and repair as well as in the deployment of transplanted neural stem cells. [Pg.182]

Accili D, Fishburn CS, Drago J, Steiner H, Lachowicz JE, Park BH, Gauda EB, Lee EJ, Cool MH, Sibley DR, Gerfen CR, Westphal H, Fuchs S (1996) A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice. Proc Natl Acad Sci USA 93 1945-1949. [Pg.184]

Agid Y, Javoy F, Glowinski J (1973) Hyperactivity of remaining dopaminergic neurones after partial destruction of the nigro-striatal dopaminergic system in the rat. Nature 245 150-151. [Pg.184]

Albrecht FE, Drago J, Felder RA, Printz MP, Eisner GM, Robillard JE, Sibley DR, Jose PA (1996) Role of the D-1A dopamine receptor in the pathogenesis of essential hypertension. J Clin Invest 97 2283-2288. [Pg.184]

Anglade P, Mouatt-Prigent A, Agid Y, Hirsch E (1996) Synaptic plasticity in the caudate nucleus of patients with Parkinson s disease. Neurodegeneration 121-128. [Pg.184]


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