Functional Genomics Consortium

Consortium for the Functional Genomics of Microbial Eukaryotes. University of Manchester, U.K URL http //www. cogeme.man.ac.uk. Analysis of the transcriptome and proteome of Saccharomyces cerevisiae (yeast) and a ntunber of plant and human fungal pathogens together with a bioinformatics centre. 

Transmembrane transport is essential to virtually all of the useful functions provided by LAB, and the presence of these transporters must reflect the evolutionary histories of the organisms in which they are found (Ren and Paulsen 2005). In earlier work we summarized some of the unusual complement of transporters encoded within LAB genomes, sequenced by the LAB genome consortium (Markarova et al. 2006 Lorca et al. 2007, 2010). In this chapter we report analyses of the distributions of the various transporters found in 11 LAB, their associations with the different transporter families, and their functional significance. We show that LAB have most unusual distributions of transporters, compared to other bacterial types, including actinobacteria. Gram (-) bacteria, and archaea, and we provide potential evolutionary explanations. 

The Encode Project Consortium (2007) Identification and analysis of functional elements in 1% of the human genome by... 

---