Formylglycinamide ribotide

The amino acid antagonists broadly act as a glutamine antagonists in the synthesis of formylglycinamidine ribotide from glutamine and formylglycinamide ribotide. 

V-Formylglycinamide ribotide, FGAR an intermediate in Purine biosynthesis (see). 

In the next reaction, formylglycinamide ribotide acquires the nitrogen 3 of the purine ring. The molecular origin of the nitrogen donor was detected by the use of an antimetabolite. When L-azaserine was added to a pigeon liver enzyme system capable of synthesizing... 

AIR. /-(S-O-Phosphono-d-D-ribofuranosyl)-lH-imidazol-5-amine 5-amino-I-ribofuranosylimidazole S -phosphate 5-aminoimidazole ribonucleotide 5-aminoimida-zole ribotide 5 -amino -1 -(5 -phosphofuranoribosy] )imida -zole. C H14N307P mol wt 295-19. C 32.55%. H 4.78%, N 14.23%, O 37.94%, P 10.49%. An intermediate in the biosynthesis of purines. Synthesis from formylglycinamide ribonucleotide Levenberg, Buchanan, J. Biol Chem. 224, 1005 (1957) Lukens, Buchanan, ibid. 234, 1791 (1959). 

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