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Formal approach to biochemical reaction kinetics

The final section of this chapter develops various methods and theories to explore control and regulation in biochemical networks. [Pg.129]


The use of kinetics to characterize the behavior of integrated biochemical systems is a more recent and less developed practice. One of the more important issues in this integrative context is the selection of an appropriate formal representation. The most common approach is simply to adopt the Michaelis-Menten Formalism that has served so well for the elucidation of isolated reaction mechanisms. However, as the discussion above showed, there are difficulties in estimating the parameters of this formalism in general, and there is a combinatorial explosion in the amount of data required to characterize the rate law by kinetic means. Thus, even if the Michaelis-Menten Formalism were appropriate in principle, there... [Pg.138]


See other pages where Formal approach to biochemical reaction kinetics is mentioned: [Pg.129]    [Pg.129]    [Pg.131]    [Pg.133]    [Pg.135]    [Pg.137]    [Pg.139]    [Pg.129]    [Pg.129]    [Pg.131]    [Pg.133]    [Pg.135]    [Pg.137]    [Pg.139]    [Pg.266]    [Pg.243]   


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