Fluoxetine Antidiabetics

The following are examples of substances that may increase the blood glucose-lowering effect and susceptibility to hypoglycemia oral antidiabetic products, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates, and sulfonamide antibiotics. 

ASA = aspirin NSAIDs = non-steroidal anti-inflammatory drugs, such as ibuprofen, naproxen, and diclofenac CNS stimulants include drugs such as pseudoephedrine, dextroamphetamine, theophylline, and caffeine MAO = monoamine oxidase CNS depressants include drugs such as benzodiazepines, barbiturates, and ethanol SSRIs = selective serotonin reuptake inhibitors, such as fluoxetine, sertraline, and paroxetine. Antidiabetic agents include drugs such as insulin, glipizide, glyburide, and metformin. 

There would seem to be little reason for avoiding concurrent use of fluoxetine, fluvoxamine or sertraline with sulphonylureas, but until more is known it would seem prudent to monitor diabetic control. The manufacturers of fluoxetine, paroxetine and sertraline warn that dosages of insulin or oral antidiabetics may need adjustment during concurrent use. ... 

MA-St nortriptyline (treatment of depression), fluoxetine (antidepressant), betahistidine (antivertigo drug), metformin (antidiabetic drug), metronidazole (antibiotic), captropril (treatment of hypertension), amantadine (antiviral, anti-parkinson), amlopidine (anti-hypertensive), gabapentin (treatment of epilepsy), zonisamide (anti convulsant), mesalamine (anti-inflamatory) 124,125... 

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