Fluorescein Disodium Salt

Other Names Fluorescein, disodium salt Fluorin 11824 Yellow 12417 Yellow 3058 Uranine Acid Yellow 73 Aizen Uranine Basacid Yellow 226 C.I. 45350 C.l. Acid Yellow 73 Calcocid Uranine B 4315 Certiqual Fluoresceine D C Yellow 8 D and C Yellow No. 8 D C Yellow No. 8 Disodium fluorescein Fluo-rectal Fluor-I-Strip Fluorescein LT Fluorescein Sodium B.P Fluorescein disodium Fluorescein sodium Fluorescein sodium salt Fluorescite Flurenate Ful-Glo Furanium Hidacid Uranine Japan Yellow 202(1) Obiturine Resorcinol phthalein sodium Sodium fluorescein Sodium fluoresceinate Soluble Fluorescein Soluble Fluoresceine BPS Ura-nin Uranin A Uranin Cone Uranin S Uranine Uranine A Uranine A extra Uranine O Uranine SS Uranine WSS 

CA Index Name Spiro[isobenzofuran-l(3H),9 -[9H]xanthen]-3-one, 3, 6 -dihydroxy-, disodium salt CAS Registry Number 518-47-8 Merck Index Number 4159 Chemical Structure 

Chemical/Dye Class Fluorescent, Xanthene Molecular Formula C2oHio05Na2 Molecular Weight 376.28 pH Range 4.0-6.0 

Solubility Freely soluble in water slightly soluble in ethanol UV-Visible ()i 3,) 491 mn, 493.5 mn, 490 nm Melting Point 300°C Synthesis Synthetic methodsi  

Zaikova, T. O. Rukavishnikov, A. V. Birrell, G. B. Griffith, O. H. Keana, J. F. W. Synthesis of fluoro-genic substrates for continuous assay of phosphatidylinositol-specific phosphohpase C. Bioconjugate Chem. 2001,12, 307-313. 

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Eosin [15086-94-9] (tetrabromofluorescein), C2QHgBi40, made by the bromination of fluorescein, is both a dye and an adsorption indicator. Eosin Y /7 7372-87-17, C2QH Br40 2Na, the disodium salt, is a biological stain. 475 -Dibromofluorescein [596-03-2], C2QH2QBr20, is used in D C Orange No. 

Fluorescein is still made commercially by the Baeyer synthesis and is very useful because of its fluorescence properties. Called uranine as the disodium salt, it is a yellow dye of low tinctorial power. Commercial suppliers call the... 

Eosin Y stands for Eosin Yellowish and it is the disodium salt of tetrabromofluorescein. There are a number of other fluorescein derivatives which are also referred to as Eosins. Eosin B or bluish is 4,5-dibromo-3,7-dinitrofluorescein. The investigator is best advised to buy dyes on the basis of structure rather than name. In the case of the other dyes in the table the literature confusion is less imposing. 

FD C Red No. 3 is principally the monohydrate of 9-(o-carboxy-phenyl)-6-hydroxy-2,4,5,7-tetraiodo-3//-xanthen-3-one disodium salt, with smaller amounts of lower iodinated fluoresceins. 

SYNS AIZEN URANINE CALCOCID URANINE B4315 9-o-CARBOXYPHEN iX-6-HYDROXY-3-ISOX.ANTHONE, DISODIUM SALT CERTIQUAL FLUORESCEINE C.I. 766 C.I. ACID YELLOW 73 C.I. 45350 DISODIUM S.M.T D C YELLOW No. 8 DISODIUM-6-HY DROXY-3-OXO-9-XANTHENE-o-BENZOATE FLUORESCEIN SODIUM B.P FLUORESCEIN, soluble FLUOR-I-STRIP A.T. FUL-GLO FUNDUSCEIN FURANIUM HIDACID UIL XINE NCI-C54706 RESORCINOL PHTHALEIN... 

SODIUM SODIUM FLUORESCEIN SODIUM FLUORESCEINATE SODIUM SALT of HYDROXY-o-CARBOXY-PHENYL-FLUORONE SOLUBLE FLUORESCEIN SPIRO(ISOBENZOFURr N)-l(3H),9 -(9H)XANTHENE-3-ONE, 3, 6 -DIHYDROXY-DISODIUM SALT URANTN URANINE A EXTRA URANINE USP XII URANINE YELLOW 11824 YELLOW ... 

Standard pH-zone-refining CCC was applied to the separation of pure components, sometimes multigram quantities, from various halogenated fluorescein (F) dyes such as 4,5,6,7-tetrachloroF, D C Orange No. 5 (mainly 4, 5 -dibromoF), D C Red No. 22 (Eosin Y, mainly the disodium salt of 2, 4, 5, 7 -tetrabromoF), D C Orange No. 10 (mainly 4, 5 -di-iodoF), FD C Red No. 3 (Erythrosine, mainly the... 

A number of derivatives of fluorescein are useful dyes. Uranin is the disodium salt of fluorescein. ChrysoUn is a salt of benzyl-fluorescein, which is formed from phthalic anhydride and benzyl-resorcinol. It dyes silk and wool a fast yellow, and is used in cotton dyeing. Eosin is the disodium salt of tetrabromo-fluorescein, which is prepared by the action of bromine on fluorescein. Its dilute alkaline solution is rose-colored, and exhibits an intense yellow-green fluorescence. Other dyes related to fluorescein are tetrabromo-dichlorofluorescein and various ethers of fluorescein and its substitution-products. The dyes of this class produce on silk and wool shades from yellow to reddish yellow, cherry-red, and purple. 

Synonyms 9-(o-Carboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3-isoxanthone Cl 45430 3, 6 -Dihydroxy-2, 4, 5, 7 -tetraiodospiro [isobenzofuran-1 (3H),9 -[9H] xanthen]-3-one disodium salt Er hrosin Erythrosin B Erythrosine FD C Red No. 3 Fluorescein, 2, 4, 5, 7 -tetraiodo-, disodium salt Food red 14 lodoeosin... 

CAS 518-47-8 EINECS/ELINCS 208-253-0 Synonyms Acid yellow 73 sodium salt (INCI) 9-o-Carboxyphenyl-6-hydroxy-3-isoxanthone, disodium salt Cl 45350 D C Yellow No. 8 3, 6 -Dihydroxyspiro [isobenzofuran-1(3H),9 -[9H] xanthen]-3-one disodium salt Disodium fluorescein Disodium-6-hydroxy-3-oxo-9-xanthene-o-benzoate Fluorescein sodium salt Naphthol yellow S Resorcinol phthalein sodium... 

Other Names Fluorescein, 2, 4, 5, 7 -tetraiodo-, disodium salt 1427 Red 1671 Red 2, 4, 5, 7 -Tetraiodofluorescein disodium salt 2,4,5,7-Tetraiodofluorescein disodium salt Acid Red 51 Aizen Erythrosine Aizen Food Red 3 C.l. 45430 C.I. Acid Red 51 C.l. Food Red 14 Calco-cid Erythrosine N Canacert Erythrosine BS Ceplac Cilefa Pink B D and C Red No. 3 D C Red No. 3 Dolkwal Erythrosine E 127 Edicol Supra Erythrosin AS Edicol Supra Erythrosine A Erythrosin Erythrosin B Erythrosin B sodium salt Erythrosin BS Erythrosine Erythrosine 3B Erythrosine B-EO Erythrosine BS Erythrosine Bluish Erythrosine Extra Erythrosine Extra Cone. A Export Erythrosine Extra Pure A Erythrosine I Erythrosine K-EO Erythrosine TB Erythrosine TB Extra Erythrosine extra bluish FD and C Red 3 FD and C Red No. 3 FD C Red No. 3 FDC Red 3 FDC Red 3 dye Food Color Red 3 Food Dye Red 3 Food Red 14 Food Red 3 Food Red No. 3 Hexacert Red No. 3 Hexacol Erythrosine BS Japan Red 3 Japan Red No. 3 Maple Erythrosine New Pink Bluish Geigy Red 1799 S 887 Synerid Tetraiodofluorescein sodium salt Usacert Red No. 3... 

Uranine (Na2(C2oHioOs)) is a disodium salt of fluorescein. Its molecular weight is 376.78. It is a commercial/medical dyestuff red-orange powder readily soluble in water. It should be noted that it causes nausea and vomiting in some cases. Clinical applications include the diagnosis of eye disorders, determination of blood circulation time and study of blood flow. 

Other Names Fluorescein, 4, 5 -dibromo-2, 7 -dinitro-, disodium salt Spiro[isobenzofuran-l(3//),9 -[97/]xan-then]-3-one, 4, 5 -dibromo-3, 6 -dihydroxy-2, 7 -dinitro-, disodium salt C.I. 45400 C.I. Acid Red 91 Dibromodi-nitrofluorescein sodium Eosin B Eosin BA Eosine B Eosine BA Eosine BN Eosine BNX Eosine I Bluish Saffrosine Simacid Nitro Eosin 24669... 

Tautomeric ( ) between spiro and open-chain forms. CA data refers to spiro-form. Strictly the name Erythrosine refers to the disodium salt. lodination prod, of Fluorescein. 

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