Floxin Otic

Brand Name(s) Floxin, Floxin Otic, Ocuflox Chemical Class Fluoroquinolone derivative... 

Oral 200, 300, 400 mg tablets Ophthalmic (Ocuflox) 3 mg/mL solution Otic (Floxin Otic) 0.3% solution... 

Floxin otic contains 0.3% (3 mg/mL) ofloxacin with ben- and water for injection. Hydrochloric acid and sodium... 

Floxin Otic Ofloxacin Hydrochloric Benzethonium chloride... 

The ophthalmic preparations should only be used in refractory cases of otitis because organism resistance may develop with widespread use. Ophthalmic preparations are also not improved by the FDA for use in the ear canal, but treating physicians may use their discretion for refractory cases. The recent introduction of Floxin and Cipro Otic drops have decreased the use of ophthalmic preparations for the treatment of refractory ear canal conditions. 

A variety of otic preparations have been reviewed here, including indications, side effects, and limitations. The ideal cerumenolytic compound has not yet been developed, nor has a cerumen replacement product. Antiseptics enjoy wide application but are limited when used in the presence of a perforated tympanic membrane. Available antifungal medications appear to be adequate for the treatment of otomycosis, although none have been approved as otic preparations. The limitations of the otic antimicrobial drops have been stated, including the potential both for organism resistance and for ototoxicity. The recent introduction of Floxin and Cipro HC products make available better otic antimicrobial drops for treatment... 

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