Fixed dose analgesics

Fixed dose combinations of atropine and analgesics and antipyretics. 

Fixed dose combinations of vitamins with analgesics. 

Fixed dose combinations of crude ergot preparations except those containing ergotamine, caffeine, analgesics, antihistamines for the treatment of migraine, headache. 

Fixed dose combination of sedatives/hypnotics/ anxiolytics with analgesics-antipyretics. 

Fixed dose. The effect that is desired can be obtained at well below the toxic dose (many mydriatics, diuretics, analgesics, oral contraceptives, antimicrobials) and enough drug can be given to render individual variation clinically insignificant. 

Phenazopyridine, an azo dye, is used as a urinary tract analgesic. However, because of toxicity, the standard use of phenazopyridine as part of a fixed-dose combination no longer seems justified. 

Although narcotic analgesics produce hypoventilation by sedation and reducing the respiratory response to carbon dioxide, prudent use of narcotics reduces postoperative pain, which facilitates coughing and maximizes vital capacity, especially after thoracic or abdominal surgery. Parenteral narcotics administered by nurses on a fixed-time basis are Ukely to produce an initial period of sedation followed by inadequate analgesia (85). When used in an episodic manner in doses that adequately control postoperative pain, narcotic... 

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