Fischerella

Three new chlorinated welwitindolinone alkaloids, e.g. 218, have been isolated from the terrestrial cyanophytes Fischerella muscicola and Fischerella major [169]. 

The toxic mushroom Russula subnigricans produces the novel polychlorinated phenyl ethers, russuphelins A-F (1928-1933), some of which (B, C, D) exhibit cytotoxicity against P388 leukemia cells (1672, 1800). Further study of this mushroom uncovered the presence of the optically active russuphelol (1934) (1801). The terrestrial cyanobacterium Fischerella ambigua has afforded ambigol C (1935) (1654), which is an isomer of the previously described ambigols A and B (1). 

Jimenez JI, Huber U, Moore RE, Patterson GML (1999) Oxidized Welwitindolinones from Terrestrial Fischerella ssp. J Nat Prod 62 569... 

Wright AD, Papendorf O, Konig GM (2005) Ambigol C and 2,4-Dichlorobenzoic Acid, Natural Products Produced by the Terrestrial Cyanobacterium Fischerella ambigua. J Nat Prod 68 459... 

Fig. 11. Phycobilisome of Masligocladus laminosus (Fischerella PCC 7603) represented in a schematic view. The structure is adapted from the PBS of Synechocystis 6701 [77] using structural and spectral data from M. laminosus biliproteins and linker polypeptides [22,31,82,97,105,135-137]. For the designation of the rod and core substructures, the nomenclature of Glazer [86] is applied.

Fig. 12. Amino acid sequence of the three biliproteins from the phycobilisome of the cyanobacterium M. laminosus (Fischerella PCC 7603) a/3-APC, a/3-C-PC, a/3-PEC and of C-PE from the cyanobacterium Fremyella diplosiphon (Calothrix UTEX 481). [PEB] is the phycoerythrobilin chromophore of C-PE the PCB-chromophores of a/8-APC, a/3-C-PC and -PEC and the PXB-chromophore of a-PEC are bound at homologous positions (to Cys and to Cys" ) and are not shown. The names of the amino acids are abbreviated according to the one-letter code (Eur. J. Biochem. (1983) 183, 9-33).

Fig, 13. Three-dimensional structure of C-phycocyanin (C-PC) o-subunit and j8-subunit (A and B) and o/3-trimer (C) derived from X-ray diffraction analysis of crystals of C-PC isolated from the cyanobacterium Mastigocladus laminosus (Fischerella PCC 7603) (101,145]. The possible positions of the additional PEB chromophores in C-PE from Fremyella diplosiphon (Calothrix UTEX 481) are adapted to the models of C-PC, using data from the amino acid sequence of C-PE [115]. Positions of the PEB chromophores at cysteine 50/61 X-X and 143a X. The beginning of the insertion 141a-o in J-C-PE is indicated by an arrow (— ). 

Raveh A, Carmeli S (2007) Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel. J Nat Prod 70 196-201... 

FischereWns. Photosystem-ll-inhibiting "allelo-chemicals from the cyanobacterium Fischerella mus-cicola. F. exhibit antifungal and herbicidal activities e.g., F. A C24Hj N202, Mr 408.58, amorphous powder. 

Nostocarboline Cyanobacterium Aphanothece Cyanobacterium Calotrix anomala Cyanobacterium Calotrix thermalis Cyanobacterium Cylindrospermum sp. Cyanobacterium Fischerella sp. Cyanobacterium Nostoc sp. 

Mo, S., Krunic, A., Santarsiero, B.D., Franzblau, S.G., and Orjala, J. (2010) Hapalindole-related alkaloids from the cultured cyanobacterium Fischerella ambigua. Phytochemistry, 71, 2116-2123. 

Park, A., Moore, R.E., and Patterson, G.M.L. (1992) Eischerindole L, a new isonitrile from the terrestrial blue-green alga Fischerella musdcola. Tetrahedron Lett., 33, 3257—3260. 

GHASEMI Y, YAZDI M T, SHAFIEE A, AMINI M, SHOKRAVI S and ZARRINI G (2004), Par-siguine, a novel antimicrobial substance from Fischerella ambigua , Pharm Biol, 42, 318-322. 

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