Finger structure

GCT-GCG-3 over the nonpermuted site. The results indicated that observations on the specihcity of zinc hngers can be extended to generalized zinc-finger structures and realized the use of zinc fingers for the design of site-specific DNA-binding proteins. ... 

Fig. 3. DNA-binding finger structure proposed for TFIIIA [21] and steroid receptors. The amino acid sequence of the glucocorticoid receptor (GR) fingers are shown. Conserved amino acids in the receptors for progesterone (PR) and oestrogen (ER) are indicated by an asterisk, whereas differences are shown.

The rate of steady state craze advance may be estimated usinp a procedure devised by Fields and Ashby A schematic view of the finger structure of the craze tip is shown in Fig. 3 a. The deforming polymer again is represented by a fluid between two rigid plates spaced a distance h apart (normal to the plane of the diagram). The radius of curvature at the tip of a void finger is h/2 in the plane normal to the craze... 

The formation of the sponge-structured membranes can be easily rationalized utilizing the description of the precipitation process given above. With finger-structured membranes the formation process is more complex and cannot entirely be described by the thermodynamic and kinetic arguments of phase separation processes. 

The solvent-precipitant interaction is apparently a particularly important parameter. One measure of this interaction is the heat of mixing a solvent and precipitant. Systems which have a large heat of mixing show high precipitation rates and a tendency to form finger-structured membranes (1 ). 

The membrane thickness comes to a minimum where permeation has the lowest value. Scanning electron microscope studies on membrane substrate structure revealed that a change from a finely pored sponge structure to a coarsely pored finger structure occurs at the point where the membrane thickness turns to go up with increase in cyclohexanone content as already shown in Figure 6. 

Figure 14.10 Picture of the transferable sample holder dedicated for in situ device fabrication, IV-measure-ments, and surface analysis in UHV without (Figure 14.10a) and with (Figure 14.10b) a mask to evaporate a metal finger structure. In Figure 14.10a a CuPc film contacted by a Au finger structure is mounted on the holder.

Fig. 5.3.14 Detailed view of seismic mass (left) and comb finger structure (right)...

A second type of zinc-finger structure, designated the C4 zinc finger (because it has four conserved cysteines in contact with the Zn ), is found in 50 human transcription factors. The first members of this class were identified as specific intracellular high-affinity binding proteins, or receptors, for steroid hormones, leading to the name steroid receptor superfamily. Because similar intracellular receptors for nonsteroid hormones subsequently were found, these transcrip-... 

The capillaries still exhibit the dense internal skin layer typical of asymmetric membranes, and a supporting finger structure (1 = 10-20 (, m) where bacteria are preferentially allocated. 

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