Filter sets parts

SOPs must be developed for label accountability with specific tolerances spelled out. Provision must be made for label security, such as locked cabinets on operating lines. Accountability sheets for other components should be provided so that reconciliation between used and finished packages can be developed. If possible, a cleaning area and shop should be set up for the cleaning of filters and parts and the disassembly and assembly of filling machines. 

The disk filter is similar to the dmm in operation, but filtration is conducted using a series of large diameter filter disks that carry the filter medium on both sides of the disk. They are connected to the main horizontal shaft and partly immersed in the feed slurry. The central shaft is connected by a set of valves which serve to provide vacuum and air as in dmm filters. As the disk sections submerge during rotation, vacuum is appHed to form a cake on both sides of the disk. The cycle of operation is similar to that in a dmm filter. One unit can have as many as 12 disks of up to 5-m diameter. Disk filters, both compact and cost effective, are used extensively in the iron ore industry to dewater magnetite concentrates. 

Acriflavin Mixture (Euflavin, 3,6-diamino-lO-metbylacridiniuni chloride) [8063-24-9] M 259.7, m 179-181 . Purified by dissolving in 50 parts of H2O, shake with a small excess of freshly ppted and washed Ag20. The mixture is set aside overnight at 0 and filtered. The cake is not washed. The pH of the filtrate is adjusted to 7.0 with HCl and evaporated to dryness. The residue is then crystd twice from MeOH, twice from H2O and dried at 120 X ,ax at 452nm has a loge value of 4.67. It is a red powder which readily absorbs H2O. The solubility is increased in the presence of proflavin. The dihydrochloride is a deep red crystn powder. It is available as a mixture of 3,6-diaminoacridinium chloride (35%) and its 10-metho-chloride (65%). [see Albert, The Acridines Arnold Press p. 346 1966 Chem Ber 45 1787 1912]. 

The first three extracts are combined and washed with 60 parts by volume of 2 N sodium carbonate solution and then with 60 parts by volume of distilled water. These washing solutions are saved and used for the yvashing of the 4th and final ethylene chloride extract. The combined ethylene chloride extracts are dried over sodium sulfate, filtered and evaporated in vacuo to a constant weight of a tan, frothy solid. One part by weight of this residue is dissolved in 1.5 parts by volume of warm methanol and the solution cooled to 5°C for 18 hours, whereby crystallization of a mixture containing principally reserpine sets in. After filtering this mixture and yvashing it with cool methanol, the filtrate is freed of Solvent in vacuo. 

Preparation of Intermediate Compound 2-Methyl-3-o-Tolyl-6-Sulfamyl-7-Chloro-4(3H)-Quinazoiinone Set up a 5-liter 3-necked flask fitted with a stirrer, condenser and a drying tube. To a stirred mixture of 100 g (0.342 mol) of powdered 4-chloro-5-sulfamyl-N-acetylanthranilic acid, 40.2 g (0.376 mol) of o-toluidine and 2.0 liters of dry toluene was added dropwise, over a period of 15 minutes, 21.7 ml (34.1 g) (0.248 mol) of phosphorus trichloride. The mixture was then refluxed for 10 hours. The solid turned somewhat gummy towards the latter part of the first hour. The mixture then became more free flowing as heating was continued. Let stand overnight. The yellow solid was filtered, washed with toluene and dried. The toluene filtrate was discarded. The dried solid was triturated with 1.5 liters of 10% sodium bicarbonate, filtered and the cake washed with water. The filtrate on acidification yielded 11.5 g of the starting acid. The damp product was dissolved in 4,5 liters of 95% ethanol and the solution treated with charcoal and filtered. On cooling filtrate yielded 69.5 g (55.5%) of the title compound, MP 271.5° to 274°C. 

A mixture of 14.1 parts of 1 -benzyl-4-cyano-4-piperidinopiperidine and 40 parts of 90% sulfuric acid is heated on a steam bath for 10 minutes. Without further heating, the mixture is stirred until a temperature of about 20°C is obtained. The mixture is then poured into 150 parts of ice-water and the resultant solution is alkalized with excess ammonium hydroxide solution. The aqueous solution is decanted from the precipitated oil. On treating this oil with 80 parts of acetone, crystallization sets in. After one hour the solid is filtered off and dried to yield 1 -benzyI-4-piperidinopiperidine-4-carboxamide melting at about 137.5°C to MO C. 

The butyl-alcoholic solution is evaporated in vacuo and the residue dissolved with gentle heating in 25 parts by volume of methyl alcohol. 100 parts by volume of acetone are added, the solution filtered and further quantities of acetone added, whereupon crystallization sets in. Yield 12.2 parts by weight of the pure product, having the melting point 177° to 179°C. 

Two methods are used to remove the dust cake, both of which require interruption of the airflow. The difference in dust-cake removal conveniently divides filters into intermittent and continuous rating. In the intermittent type the pressure increases (with time) up to a pre-arranged level. The airflow is then stopped and the fabric is mechanically shaken. In the continuously rated filter the pressure drop rises to a low set point, after which it remains constant across the filter as a whole. The cleaning is done by isolating a part of the filter from the air stream and that section is cleaned. 

Polychlorotrifluoroethylene (PCTFE) is ordinarily prepared by emulsion polymerization. A polymer suitable for thermal processing requires coagulation, extensive washing, and postpolymerization workup. Coagulation to provide a filterable and washable solid is a slow, difficult process and removal of surfactant is an important part of it. Complete removal may be extremely difficult depending on the extent of adsorption to the polymer particles. Consequently we set out to develop a suspension polymerization process, which would be surfactant-free and afford an easily isolated product requiring a minimum of postreaction workup. 

Then the multivariable IMC controller is set equal to the invertible part times a filter matrix which slows up the closedloop response to give the system more robustness. The filter acts as a tuning parameter (tike setting the closedloop time constant in the SISO case in Chap. 8). 

---