Fibrous dysplasia

G, alpha Insertions/dele- syndrome fibrous dysplasia of bone cafe-au-lait skin lesions sexual precocity pituitary, thyroid, or adrenal tumors Albright s hereditary with constitutive cAMP production Inactivating G a (86-89)... 

Shenker, A., Weinstein, L. S., Sweet, D. E., and Spiegel, A. M. (1994) An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. J. Clin. Endocrinol. Metab. 79, 750-755. 

An activating Gs alpha mutation is present in fibrous dysplasia of bone in the Me Cune-Albright syndrome. J Clin... 

Fibrous dysplasia Radiology and bone histology 74 37 Pritchard (P37)... 

Precocious puberty may be associated with polyostotic fibrous dysplasia, which causes hyperphosphatasemia (A5). Some patients with precocious puberty suffer from convulsive disorders (L17), for which they receive anticonvulsant medication, resulting in osteomalacia and elevated serum alkaline phosphatase activities. Precocious puberty has also... 

B14. Benedict, P. H., Endocrine features in Albright s syndrome (fibrous dysplasia of bone). Metabolism 11, 30-45 (1962). 

Lane JM, Khan SN, O Connor WJ, et al Bisphosphonate therapy in fibrous dysplasia. Clin Orthop... 

Matarazzo P, Lala R, Masi G, et al. (2002). Pamidronate treatment in bone fibrous dysplasia in children and adolescents with McCune-Albright syndrome. J Pediatr Endocrinol Metab 15(suppl 3) 929-937. 

Fig. 21.1. Fibrous dysplasia. Shepherd s crook deformity. The attempted internal fixation has failed...

Fibrous dysplasia is a developmental anomaly ofbone in which the normal medullary space is replaced by fibroosseous tissue (Smith and Kransdorf 2000). It may affect a single bone (monostotic - 75% cases) or... 

Fig. 21.4. Polystotic fibrous dysplasia prefracture, immediately postfracture and healed several months later with residual deformity...

Fig 13.12. Fibrous dysplasia in a young woman complaining of constant tickling in her upper cheek. Exams done by ENT doctor and dentist were without any result... 

A sclerotic border of a bony lesion is more obvious with MDCT than with radiograms. The presence or absence of such a sclerotic border may allow narrowing the differential diagnosis. Chondroblastomas, nonossifying fibromas, and fibrous dysplasia typically are surrounded by a sclerotic rim, while eosinophilic granulomas and osteolytic metastases are not (Fig. 35.8 Gould et al. 2007). 

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