Silastic fibronectin-coated

The embolization process on the fibronectin-coated PVC surface was quite different than the embolization process on fibronectin-coated Silastic. On fibronectin-coated PVC, 97% of the deposited thrombus [both platelets and fibrin(ogen)] were shed after 120 min of blood contact, while on fibronectin-coated Silastic only 75% of the deposited platelets and none of the fibrin(ogen) was released. This behavior is consistent with the observations shown in Figures 17 and 18 (fibronectin-coated PVC at 30 min and... 

Figure 18. Fibronectin-coated Silastic after 30 min of blood contact. Large adherent thrombus (center) is beginning to embolize. Surrounding surface coverage appears to be mostly fibrin with a few adherent platelets.

On Silastic, however, the thrombotic response to the fibronectin-coated surface was quite different than the response to the 7-globulin-coated surface. Initially, more fibrin(ogen) was deposited on the fibronectin-coated surface, whereas platelet adhesion was greatly diminished. At later times of blood contact, platelet adhesion to the fibronectin-coated surface increased... 

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