Fibrinolysis pathological

Y. P. Konttiaen, Fibrinolysis—Chemisty, Physiology, Pathology, Oystar Ah Pubhshers, Tampere, Einland, 1968, pp. 1—643. 

In some pathological states, fibrinolysis is hyperactive and inhibitors have a hemostatic value. 

Some pathological conditions have been suggested to result from inhibition of fibrinolysis. Lieberman... 

Kininogenases are inhibited by numerous substances. In particular, the inhibition of kallikrein has been thoroughly studied since its discovery. One of the inhibitors, a polyvalent inhibitor of kallikrein and trypsin extracted from bovine lungs, was used with partial success in the treatment of experimental and clinical pathological conditions where activation of different proteolytic and esterolytic enzymes is assumed to play an important rdle in pancreatitis, peritonitis, the Schwartzmann phenomenon, spontaneous fibrinolysis, endotoxin shock, etc. 

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