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Fibrinogen receptors platelet aggregation

CD41/61 representing the GPIIb-IIIa complex, which is a receptor for fibrinogen, von Willebrand factor, fibronectin, and vitronectin. This complex is essential for platelet aggregation. [Pg.156]

An in vitro or ex vivo measure of drug effect, for example, mean inhibitory concentration (MIC) of an antimicrobial against bacterial culture inhibition of ADP-induced platelet aggregation with a fibrinogen receptor antagonist. [Pg.213]

Conformational change in GPIIb/IIIa receptor allows binding to fibrinogen through RGD and KQAGDV amino acid sequences Platelets aggregate... [Pg.239]

Mechanism of Action A glycoprotein Ilb/IIIa receptor inhibitor that rapidly inhibits platelet aggregation by preventing the binding of fibrinogen to GP Ilb/IIIa receptor sites on platelets. Therapeutic Effect Prevents closure of treated coronary arteries. Prevents acute cardiac ischemic complications. [Pg.1]

Mechanism of Action An aggregation inhibitor that inhibits the release of adenosine diphosphate from activated platelets, which prevents fibrinogen from binding to glycoprotein Ilb/IIIa receptors on the surface of activated platelets. TherapeuticEffect Inhibits platelet aggregation and thrombus formation. [Pg.1213]

Blockers/inhibitors of platelets receptors GP Ilb/IIIa (integrin allb(33) (abeiximab, tirofiban, eptifibatide) Prevent the link of fibrinogen with platelet receptors inhibiting platelet aggregation in front of different agonists... [Pg.39]

See other pages where Fibrinogen receptors platelet aggregation is mentioned: [Pg.35]    [Pg.722]    [Pg.16]    [Pg.168]    [Pg.169]    [Pg.145]    [Pg.85]    [Pg.98]    [Pg.136]    [Pg.151]    [Pg.128]    [Pg.239]    [Pg.241]    [Pg.302]    [Pg.579]    [Pg.98]    [Pg.163]    [Pg.56]    [Pg.63]    [Pg.239]    [Pg.248]    [Pg.373]    [Pg.373]    [Pg.263]    [Pg.119]    [Pg.59]    [Pg.246]    [Pg.155]    [Pg.264]    [Pg.753]    [Pg.767]    [Pg.247]    [Pg.744]    [Pg.115]    [Pg.411]    [Pg.776]    [Pg.158]    [Pg.4]    [Pg.5]    [Pg.32]    [Pg.33]    [Pg.41]    [Pg.85]    [Pg.128]   
See also in sourсe #XX -- [ Pg.175 ]



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Fibrinogen

Fibrinogen platelets

Fibrinogen receptor

Platelets receptors

Receptors aggregation

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