Ferrocene amide

Anion binding by neutral ferrocene-amide receptors 66... 

Table 4 Electrochemical data and group I metal cation dependence of ferrocene amide aza crown ethers and model analogues.

ANION BINDING BY NEUTRAL FERROCENE-AMIDE RECEPTORS... 

Receptor 93 incorporates a zinc porphyrin backbone with four ferrocene amides [65]. This shares the design of the cobaltocenium receptor 4, except that now a zinc atom occupies the centre of the porphyrin. The Lewis acid metal centre provides an additional binding site for anion recognition. In dichloro-methane solution no significant anion-induced shifts in the lH NMR signals of the amide protons were seen in the free-base precursor of 93, whereas the... 

Electrochemical Data and Group IA Metal Cation Dependence of Ferrocene Amide Aza Crown Ethers and Model Analogs... 

Table 6-2. Electrochemical data for ferrocene amide bis-azacrown ethers and their group lA metal complexes compared with Fc(CONMe2)2, 59...

Grossel, M.C. Goldspink. M.R. Hriljac. J.A. Weston. S.C. Metallocene-bridged cryptands. 2. Solid-state studies of some ferrocene amides and their cryptand analogs. Organometallics 1991. 10. 851-860. 

The scope of aminocarbonylations was extended by the works from various groups. For example, Skoda-Fbldes and Kollar studied the carbonylation reactions of ferrocene derivatives in the presence of Pd(OAc)2/PPh3 [126-128]. Ferrocene amides and novel ferrocene a-ketoamides were synthesized in good yields based on palladium-catalyzed aminocarbonylation or double carbonylation of iodofer-rocene at 40-50 bar of CO. The double-carbonylated products were favored at 40-60 °C and amides were produced almost exclusively at 100 °C, as the selectivity of the reaction with less sterically hindered secondary amines is highly dependent on the reaction temperature. Analogous aminocarbonylation reactions of l,l -diiodoferrocene led to I -iodo-ferrocenecarboxamides and I -iodo-ferro-ceneglyoxylic amide-type products. 

Fig. 8 Plots of the lateral D values of the ferrocene-amide derivatives (see structure D in Figure 7), CieFc and C12FC vs. MMA measured on the 0.05 M HCIO4 subphase containing (A) 0, (B) 20, and (C) 40 wt% glycerol. The viscosities of these solutions were 1.1, 1.9, and 3.7 cP, respectively (from Ref. 54).

The distances of the carbonyl carbon to the Cp rings for all structurally characterized Fc-peptides are well within estabhshed bond distances for a normal C-C single bond in Fc-amides [range d(C-C) = 1.43-1.507 A]. Fmthermore, the amide C(0) N group is planar in all Fc-amino acids and Fc-peptides, and the carbonyl C=0 distances compare well wifli simple ferrocene amides. Similarly, the bond distances and angles of the Fc moiety itself are well within established parameters for ferrocene derivatives. ... 

R. rhodochrous PA-34 Ferrocene nitrile, ferrocene acetonitrile (6-nitrile hexyl)ferrocene Amide and acid analogues Chemoenzymatic synthesis of ferrocene derivatives [96]... 

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