Felbamate administration

Thompson CD, Gulden PH, Macdonald TL. Identification of modified atropaldehyde mercapturic acids in rat and human urine after felbamate administration. Chem Res Toxicol 1997 10 457-462. 

Felbamate. Felbamate, chemically 2-phenyl-1,3-propanediol dicarbamate (10), is well absorbed after oral administration (68). Felbamate is distributed to all tissues and has been metabolized by several pathways in ani-... 

Dosing and Administration. A therapeutic range for felbamate has not been established. The drug is dosed to clinical response. If felbamate is used as monotherapy, the dose is initiated at 1200 mg/day (15 mg/kg in children) and then is increased by 600 mg every 2 weeks up to a maximum dose of 3600 mg (45 mg/kg in children). 

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