Feedback, lack

Hazardous Condition Missing guard Poor Housekeeping Defective tools Equipment failure No Safety Data Sheets Hidden root causes Poor work procedures No follow-up/feedback Lack of training Poor safety management... 

Regardless of the method(s) you select, it s important to get feedback from the full spectrum of people affected by the pilot. No matter how "tuned in" fadlity managers maybe, they may lack the day-to-day perspective you need... 

Feedback modification efforts arc targeted information programs that address the lack of awareness of people about the consequences, the belief being that if people are aware or educated about the negative consequences of such behavior, it is more likely that they can be convinced to engage in behavior... 

These mutants lack feedback inhibition and are used for the production of many amino adds. 

Auxotrophic mutant lack one or more enzymes involved in the synthesis of amino acids (such as tyrosine). This prevents accumulation of the amino acid and thus avoids feedback inhibition of enzymatic steps in the L-phenylalanine pathway. 

The lack of structural similarity between a feedback inhibitor and the substrate for the enzyme whose activity it regulates suggests that these effectors are not isosteric with a substrate but allosteric ( occupy another space ). Jacques Monod therefore proposed the existence of allosteric sites that are physically distinct from the catalytic site. Allosteric enzymes thus are those whose activity at the active site may be modulated by the presence of effectors at an allosteric site. This hypothesis has been confirmed by many lines of evidence, including x-ray crystallography and site-directed mutagenesis, demonstrating the existence of spatially distinct active and allosteric sites on a variety of enzymes. 

In Ref. 30, the transfer of tetraethylammonium (TEA ) across nonpolarizable DCE-water interface was used as a model experimental system. No attempt to measure kinetics of the rapid TEA+ transfer was made because of the lack of suitable quantitative theory for IT feedback mode. Such theory must take into account both finite quasirever-sible IT kinetics at the ITIES and a small RG value for the pipette tip. The mass transfer rate for IT experiments by SECM is similar to that for heterogeneous ET measurements, and the standard rate constants of the order of 1 cm/s should be accessible. This technique should be most useful for probing IT rates in biological systems and polymer films. 

Analysis of compound dynamic instabilities. As mentioned in the previous section, most of the compounded and feedback effects are built into computer codes for analyzing dynamic instabilities. These computer codes can be used to analyze compound dynamic instabilities such as BWR instability and parallel-channel instability. However, thermal instability between transition boiling and film boiling cannot be analyzed, because of the lack of phenomenological correlation of transition boiling. 

Wersinger SR, Haisenleder DJ, Lubahn DB, Rissman EF (1999) Steroid feedback on gonadotropin release and pituitary gonadotropin subunit mRNA in mice lacking a functional estrogen receptor a. Endocrine 11 137-143... 

In order to estimate the flux through the SMM cycle and to explore its function, a computer model of methionine metabolism in mature Arabidopsis rosette leaves was developed based on data from radiotracer experiments and on metabolite contents. This model suggested that the cycle serves to stop accumulation of AdoMet, rather than to prevent depletion of free methionine, as proposed by Mudd and Datko.54 Because plants lack the AdoMet feedbacks on MTHFR and AdoMet synthetase that regulate AdoMet pool size in other eucaryotes, the SMM cycle may be the main mechanism whereby plants achieve short-term control of AdoMet level. MMT knockouts of maize and Arabidopsis recently became available, and these can now be used to further investigate the role of the SMM cycle, and to test the predictions of the model. 

All these waveguiding films lack one important feature that would be necessary for true lasing They do not have a resonator for optical feedback that would lock the optical modes traveling in the gain direction. The thin-film waveguide confines the optical modes in one direction (in the vertical), but in the other two dimensions the modes have translational and rotational symmetry. The incorporation of resonator structures into the thin films in order to get true organic solid-state lasers will be described next. 

Low afterpulsing due to ion or photon feedback to the photocathode and low prepulsing due to photoelectron generation from dynodes. The lack of a direct line of... 

The explanation for this phenomenon is that in the prepubertal phase the amount of testosterone that is secreted is not sufficient to cause development of the male genitalia, which is normally stimulated by dihydrotestosterone. However, at puberty the secretion of testosterone increases. The increase is large in this syndrome, because lack of dihydrotestosterone decreases the extent of the feedback inhibition of the hormone secretions by the pituitary so that more gonadotrophins are released which stimulate, markedly, the rate of testosterone secretion and hence its concentration in the blood. At these high levels, testosterone has sufficient androgenic effects to stimulate development of the external genitalia. 

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