Fast pain

Compare and contrast fast pain and slow pain... 

Fast pain may be described as sharp or prickling pain (see Table 8.2). This pain is perceived first (within 0.1 sec) as it is carried by the more rapidly... 

Lethal Arrhythmias. Arrhythmias are a second significant source of cardiovascular problems. An arrhythmia is an abnormal or irregular heart rhythm. Bradyarrhythmias result in heart rates that are too slow tachyarrhythmias cause abnormally fast rates. A bradyarrhythmia can be debiUtating, causing a person to be short of breath, unable to climb stairs, black out, or even to go into cardiac arrest. Tachyarrhythmias can be un settling and painful at best, life-threatening at worst. 

Symptoms typical of tachyarrhythmias include palpitations, dizziness, lightheadedness, shortness of breath, chest pain (if underlying CAD is present), near-syncope, and syncope. Patients commonly complain of palpitations often the complaint is "I can feel my heart beating fast" or "It feels like my heart is going to beat out of my chest."... 

MN is a 48-year-old man with a history of hypertension and smoking who presents to the clinic for evaluation of his cholesterol. He denies having chest pain or history of myocardial infarction, stroke, or peripheral artery disease. He has no siblings and both parents are alive with no history of CHD. MN says that he smokes about 1 pack of cigarettes per day. He does not exercise on a regular basis. He has been fasting for approximately 11 hours. 

Transition to oral analgesics as the patient improves choose an oral agent based on previous history, anticipated duration, and ability to swallow tablets if sustained-release products are used, a fast-release product is also needed for breakthrough pain... 

In broilers of modern fast growing, meat production genotypes, most deaths are due to sudden heart failure and parasite infections (see also Chapter 12). Also such genotypes suffer from leg disorders (perosis, tibial dyschondroplasia, etc.) and muscle diseases to such an extent that they have difficulty in walking normally. They are thought to suffer severe pain and consequently spend much longer lying down. This in turn may lead to serious breast blisters. 

In a typical situation, as illustrated in Figure 24.3, the composition and flow rate of each feed stream (gas at the bottom and liquid at the top) are specified, directly or indirectly this enables evaluation of the quantities pAin, cAin, cB in, L, and G. The unknown quantities to be determined, in addition to h (or I, the packed volume), are Pa,out and c, our The determination involves use of the rate law developed in Section 9.2 for an appropriate kinetics regime (1) reaction in bulk liquid only (relatively slow intrinsic rate of reaction), or (2) in liquid film only (relatively fast reaction), or (3) in both bulk liquid and liquid film. For case (2), cA = 0 throughout the bulk liquid, and the equations developed below for the more general case (3), cA 0, are simplified accordingly. 

The simplex algorithm is conceptually a very simple method. It is reasonably fast for small numbers of parameters, robust and reliable. For high dimensional tasks with many parameters, however, it quickly becomes painfully slow. Also, the simplex algorithm does not deliver any statistical information about the parameters, e.g. it is possible to fit parameters that are completely independent of the data. The algorithm delivers a value without indicating its uselessness. 

Rare genetic absence of lipoprotein lipase results in excess triglyceride in the blood and its deposition in several tissues, including liver, skin, and pancreas. Orange-red eruptive xanthomas over the mucous membranes and skin may be seen. Abdominal pain and acute pancreatitis may occur. Fasting chylomicronemia produces a milky turbidity in the serum or plasma. 

Here are the positive talking points for morphine. First, morphine is a highly effective agent for the treatment of severe pain. It is generally given by injection and relief is very fast. Second, morphine is widely available. Finally, morphine is cheap. For the latter two reasons, morphine is nsed worldwide, not just in developed countries that can afford more expensive (and sometimes extremely expensive) medications. 

Chloroprocaine is used in situations requiring fast-acting pain relief. It is also used in infiltration anesthesia, blocking peripheral nerve transmission, and in spinal and epidural anesthesia. Nesacaine is a synonym for chloroprocaine. 

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