Farnesyl pyrophosphatase

Meigs T. E. and Simoni R. D. (1997) Farnesol as a regulator of HMG-CoA reductase degradation characterization and role of farnesyl pyrophosphatase. Arch. Biochem. Biophys. 345, 1-9. 

FIGURE 30.6 Examples of protein crystals. From left to right (3-secretase inhibitor complex human farnesyl pyrophosphatase in complex with the nitrogen-containing bisphosphonate drug zoledronic acid Crystals of the Abl kinase domain in complex with imatinib - Source Courtesy of S.W. Cowan-Jacob, Novartis Institutes for BioMedical Research crystal of a Cdk2 inhibitor complex. 

Farnesyl pyrophosphatase synthase inhibitor 63 Modeller Gold 1009 diverse, druglike 14 — 60(1) — [18]... 

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See also in sourсe #XX -- [ ]

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