Family search

EXA (exact) search retrieves the input stmcture and its stereoisomers, homopolymers, ions, radicals, and isotopicaHy labeled compounds. EAM (family) search retrieves the same stmctures as EXA, plus multicomponent compounds, copolymers, addition compounds, mixtures, and salts. SSS (substmcture) search uses a range of possible substituents and bonds in the input stmcture. CSS (closed substmcture) search is a more restrictive... 

Wu, C. H., Zhao, S., Chen, H. L Lo, C. J. McLarty, J. (1996). Motif identification neural design for rapid and sensitive protein family search. Comput Appl Biosci 12,109-18. 

Xuan, Z. Y., W. R. McCombie, and M. Q. Zhang. 2002. GFScan A gene family search tool at genomic DNA sequence level. Genome Res 12 1142-9. 

The production stage occurs when the system is ready for production. New components can be planned in this stage. An incoming component is first coded. The code is then sent to a part family search routine to find the family to which it belongs. Because the standard plan is indexed by the family number, the standard plan can be easily retrieved from the database. Because the standard... 

A structure search of chemical substances can be performed in the chemical structure databases. The structure query can be input using a graphical structure editor. The following search methods are possible, depending on the type of structure database. The structure search capabilities depend on the software system. Here, the focus is on the implementation of STN International exact structure search, family search, substructure search, similarity search, generic (Markush) search, and reaction search. 

Like the Exact Structure Search, Family Searches (FAM) also do not allow further substitutions. The result consists of compounds that match exactly the request, and also of multicomponent substances as well as salts, such as the potassium salt of piceol in Fig. 100. 

Fig. 100. Example for a compound, found by Family Search for piceol...

Unlike the Registry File, which contains single, exactly defined compounds, MARPAT provides numerous compounds under a single structure. Since only generic structures are contained in MARPAT, Exact (EXA) and Family Searches (FAM) cannot be executed - it is only possible to conduct Closed Structure Searches (CSS) and Substructure Searches (SSS) (Sect. 7.2.1). 

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