Factors influencing protein-polyelectrolyte

Factors Influencing Protein-Polyelectrolyte Complexation and Structures of the Protein-Polyelectrolyte Complexes... 

Factors influencing Protein-Polyelectrolyte Complexation 261 153,2 pH or Protein Charge... 

For instance, denaturation and partial hydrolysis of proteins oppositely influence their incompatibility with other biopolymers (Tolstoguzov 1991). Most biopolymers are polyelectrolytes. Factors such as pH and salt concentration affect their interactions with one another, with the solvent and their compatibility. For instance, when the pH is shifted to their isoelectric point (lEP), the thermodynamic incompatibility of proteins is usually enhanced by self-association of the protein molecules. Generally, protein-neutral polysaccharide mixtures separate into two phases when the salt concentration exceeds 0.15 M. 

---