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Factor inhibiting HIF-1

As a second means of hypoxic HIF-1 regulation, HIF-1 activity is mediated through the action of an oxygen-dependent asparaginyl hydroxlase, sometimes referred to as factor inhibiting HIF-1 (FIH). The FIH... [Pg.673]

M, Ruas JL, Wilkins S, Bilton RL, Brismar K, Whitelaw ML, Pereira T, Gorman JJ, Ericson J, Peet DJ, Lendahl U, Poellinger L. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways. Proc Natl Acad Sci USA 2008 105 3368-3373. [Pg.554]

Two oxygen-sensing mechanisms help cells respond to oxygen deprivation one mechanism activates transcription of hypoxia-induced factor 1 (HIF-1), and the other promotes stabilization of HIF-1 by inhibiting its proteasomal degradation. [Pg.621]

See other pages where Factor inhibiting HIF-1 is mentioned: [Pg.335]    [Pg.123]    [Pg.524]    [Pg.56]    [Pg.335]    [Pg.123]    [Pg.524]    [Pg.56]    [Pg.338]    [Pg.728]    [Pg.444]    [Pg.674]    [Pg.675]    [Pg.3790]    [Pg.227]    [Pg.265]    [Pg.361]    [Pg.533]    [Pg.67]    [Pg.68]    [Pg.315]    [Pg.346]    [Pg.347]    [Pg.374]    [Pg.671]    [Pg.49]    [Pg.439]    [Pg.458]    [Pg.124]    [Pg.48]    [Pg.52]    [Pg.122]    [Pg.665]    [Pg.675]    [Pg.677]    [Pg.533]    [Pg.450]    [Pg.86]    [Pg.229]    [Pg.26]    [Pg.30]    [Pg.252]    [Pg.737]    [Pg.47]    [Pg.3408]    [Pg.3413]    [Pg.204]    [Pg.382]    [Pg.78]    [Pg.96]   
See also in sourсe #XX -- [ Pg.123 ]



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Factor inhibition

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