F/? -2-bromobutane

Label a series of ten clean and dry test tubes (10 X 75 mm test tubes may be used) from 1 to 10. In each test tube, place 2 mL of a 15% Nal-in-acetone solution. Now add 4 drops of one of the following halides to the appropriate test tube (1) 2-chlorobutane, (2) 2-bromobutane, (3) 1-chlorobutane, (4) 1-bromobutane, (5) 2-chloro-2-methylpropane (f-butyl chloride), (6) crotyl chloride CH3CH = CHCH2CI (see Special Instructions), (7) benzyl chloride (a-chlorotoluene) (see Special Instructions), (8) bromobenzene, (9) bromocyclohexane, and (10) bro-mocyclopentane. Make certain you return the dropper to the proper container to avoid cross-contaminating these halides. 

Altai, M. Munoz Embid, J. Velasco, I. Excess enthalpies and excess volumes of (1-bromobutane or 1-iodobutane -f 1 -chloropropane or 1 -chloropentane) and of (1 -iodobutane + bromoethane or 1 -bromobutane) at the temperature 298.15 K /. Chem. Thermodyn. 1994, 26,609-615... 

A suspension of selenium dioxide in tetrahydrofuran added slowly at 20° to an ethereal soln. of n-butylmagnesium bromide prepared from 1-bromobutane and Mg, and stirring continued 1 hr. dibutyl selenide. Y 48-62%. F. e. s. A. Arase and Y. Masuda, Chem. Lett. 1975, 1331. 

BROMO BUTANE or n-BROMOBUTANE (109-65-9) Forms explosive mixture with air (flash point 65°F/18°C). Violent reaction with strong oxidizers, strong acids. Incompatible with organic anhydrides, acrylates, alcohols, aldehydes, alkylene oxides, substituted allyls, cresols, caprolactam solution, epichlorohydrin, ethylene dichloride, glycols, isocyanates, ketones, maleic anhydride, nitrates, nitromethane, phenols, vinyl acetate. May accumulate static electrical charges may cause ignition of its vapors. 

Finally, as foreshadowed in Chapter 7 (Scheme 7.24 ft, the Hofmann elimination) and Chapter 8, Part I, Section F, A. W. Hofmann (1818-1895) pointed out that elimination from ammonium ions yielded the least highly substituted alkene rather than the most highly substituted alkenes (the Saytzeff elimination). Thus, as shown in Scheme 10.47, when 2-aminobutane is exhaustively methylated with iodomethane (ICH3) and treated with base, there is more ehmination to yield 1-butene (about 60%) than when, for example, the same elimination reaction is effected on 2-bromobutane (about 20%). It has been argued that this result comes about because the base is closely associated with the positively charged ion and the hindered environment favors loss of the proton from the primary carbon. 

Fig. 4.6. Element selective detection of the gas chromatographic separation of a mixture of ethanol (a), i-propanol (6), carbon tetrachloride (c), 1,2-dichloroethane (d), nitroethane (c), n-bromobutane (f), tetrachloroethylene (g), 1,2-dibromoethane (A), bromobenzene (i). phenol ( ). and chlorobenzaldehvde (k).

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