Extracellular signalling molecule

One of the most studied examples of signaling with membrane lipids is provided by the phospho-inositide cascade, which is pictured in Fig. 11-9. Six or more phosphate esters of phosphatidylinositol (PI) are generated by the action of kinases.219 220 More than 100 extracellular signaling molecules activate specific isozyme forms of phospholipase C,221-224 releasing 20 or more different inositol phosphates from these... 

Cell signaling In multicellular organisms there is a need for the cells to communicate with one another in order to coordinate their growth and metabolism. The principal way by which cells communicate with each other is by means of extracellular signaling molecules or hormones. These molecules are synthesized Instant Notes in Biochemistry 2nd Edition, B.D. Hames N.M. Hooper, (c) 2000 BIOS Scientific Publishers Ltd, Oxford. 

Fields, R. D., and Stevens, B. (2000). ATP An extracellular signaling molecule between neurons and glia. Trends Neurosci. 23, 625-633. 

Extracellular signaling molecules regulate interactions between unicellular organisms and are critical regulators of physiology and development in multicellular organisms. 

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