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Expression vectors tobacco mosaic virus

The majority of viruses that infect plants have single-stranded, positive-sense RNA genomes. It has therefore been necessary to use infectious cDNA clones for the in vitro manipulation of RNA viruses, allowing them to be developed as effective tools for the commercial production of target proteins in plants. This approach has also been used to study the genetic and metabolic profiles of both viruses and their host plants. Siegel [14] conceptualized the potential use of RNA viruses as expression vectors. Brome mosaic virus (BMV) and Tobacco mosaic vims (TMV) were the first two RNA viruses to be converted into expression vectors. These vectors have since been pro-... [Pg.78]

NT009 Wu, L., L. Jiang, Z. Zhou, et al. Expression of foot-and-mouth disease virus epitopes in tobacco by a tobacco mosaic virus-based vector. Vaccine 2003 21(27-30) 4390-4398. [Pg.340]

Kang, T.J., Kang, K.H., Kim, J.A., Kwon, T.H., Jang, Y.S., andYang, M.S. (2004). High-level expression of the neutrahzing epitope of porcine epidemic diarrhea virus by a tobacco mosaic virus-based vector. Protein Expr. Purif. 38(1) 129-135. [Pg.24]

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Expression vector

Mosaic

Mosaicism

Mosaicity

Tobacco mosaic virus

Viruses tobacco mosaic virus

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