Exposure performance

Using the nonlinear model substituting 0.915 p.gcm (the DFR value from the model 1 day after application) into Equation (6) yields a dose of 1.05 mgkg day" and an MOL from Equation (5) of 47, below the required value of 100 for margin of exposure. Performing the same calculation on the day 2 data gives a dose of 0.344 mg kg day and an MOE of 145, which is above the level of 100 required to establish a safe re-entry level. Therefore, a 2-day period is adequate to ensure worker safety. The observed values of 0.936 and 0.234 qg cm for days 1 and 2 match closely the values predicted by the model. 

The data support specifically the use of epoxy-containing plasticizers in all systems for exterior exposure. Performance is enhanced by using n-alkyl phthalates and 2-ethylhexyl analogs as opposed to plasticizers derived from oxo-alcohols. 

During the preparation of hazardous drugs, use a ventilated cabinet to reduce the potential for occupational exposure. Performance test methods and criteria for BSCs may be found in Primary Containment for Biohazards Selection, Installation and Use of Biological Safety Cabinets, second edition, CDC/NIH, 2000. A current field certification label should be prominently displayed on the ventilated cabinet per NSF/ANSI49. 

Improved versions of the high performance resin systems continue to be developed (245,246). Toughening of epoxies and epoxy vinyl esters has emerged as an area for investigation (247). Lower styrene content vinyl esters have been developed to reduce worker exposure. Performance enhancements with epoxy and vinyl ester nanocomposites have been reported in the literature, but commercialization has not been yet realized. 

REAGENT (Solids in saturated solution unless indicated otherwise) EXPOSURE CHEMICAL EXPOSURE PERFORMANCE S = Satis. M- Marginal U= Unsatis. PERMEABILITY (gm./24 hr./ 100 sq. in/mil)... 

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