Experimental synthesis

Virtual screening allows the scope of screening to be extended to external databases. When this is done, increasingly diverse hits can be identified. The application of virtual. screening techniques before or in parallel with HTS hclp.s to reduce the assay-to-lcad attrition rate observed from HTS. In addition, virtual screening is faster and less expensive than experimental synthesis and biological testing. 

Of the 273 varieties of whiskers included in Appendix 2, most are singlecrystal whiskers. Polycrystal fibers and aggregates composed of fibrils are also known and have been produced. Stellate or spherulitic aggregates are common, although they are mostly unplanned—the result of rapid growth during experimental synthesis studies and in manufaeturing. 

March Experimental synthesis work was initiated for the herbicide project. 

Domanik K. J. and Holloway J. R. (2000) Experimental synthesis and phase relations of phengitic muscovite from 6.5 to 11 GPa in a calcareous metapelite from the Dabie mountains. China. Lithos 52, 51-77. 

Low-temperature (3-20 °C) experimental synthesis of nontronite has been accomplished by precipitation and aging of iron hydroxides with coprecipitated silica under reducing conditions and at near neutral pH values of 7-9 (Harder, 1976). Iron smectites sometimes coexist with mixed-layer nontronite/celadonite (e.g., Sayles et al., 1975 Honnerez et al., 1983). 

Tetravalent anion groups. A complete solid solution between OHAp and britholite-(Y), indicative of extensive substitution of P04 by Si04" , has been confirmed by data from both natural apatites and experimental synthesis (Ito 1968 Felsche 1972 Rouse and Dunn 1982 Roeder et al. 1987 Ronsbo 1989 Liu and Comodi 1993 Comodi et al. 1999). Two coupled substitutions of the type ... 

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