Exocrine gland peptide

IgA. IgA (Fc = a) (Fig. 7-9) is found in exocrine gland secretions (milk, saliva, tears), where it protects mucous membranes (e.g.. in the respiratory tract). It is present in the serum as a monomer at a concentration of I to 2 mg/mL. but humans secrete about I g of the dimer per day in the mucosal fluids. Secretory IgA consists of two IgG-like units linked together at the Fc regions by a peptide known as the secretory fragment and a J fragment. The secretory fragmenl... 

Kimoto H, Haga S, Sato K, Touhara K (2005) Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons. Nature 437 898-901 Kinnamon SC, Margolskee RF (1996) Mechanisms of taste transduction. Curr Opin Neurobiol 6 506-513... 

Kimoto H, Haga S, Sato K, Touhara K (2005) Sex-specific peptides from exocrine glands stimulate mouse vomeronasal sensory neurons. Nature 437 898-901 Kimoto H, Sato K, Nodari F, Haga S, Holy TE, Touhara K (2007) Sex- and strain-specific expression and vomeronasal activity of mouse ESP family peptides. Curr Biol 17 1879-1884 Kobayakawa K, Kobayakawa R, Matsumoto H, Oka Y, Imai T, Ikawa M, Okabe M, Ikeda T, Itohara S, Kikusui T, Mori K, Sakano H (2007) Innate versus learned odour processing in the mouse olfactory bulb. Nature 450 503-508... 

Electrical stimulation of the periaqueductal gray matter has produced naloxone-reversible analgesia that displays cross-tolerance with morphine analgesia and releases endogenous opioid peptides into the CSF. Enkephalins also exist in cells whose functions relate to bowel motility (nerve plexuses and exocrine glands of the stomach and intestine). 

---