Pharmaceutical excipient

Since surface active betaine esters can be degraded under mild conditions and the hydrolysis products, i.e., the amino acid betaine and a long-chain alcohol can be expected to be less toxic than the intact surfactant, these am-phiphiles are interesting candidates for use in applications where surfactant toxicity is an issue. Surface active betaine esters have been evaluated as temporary bactericides [34] and have been studied as potential candidates for use as pharmaceutical excipients (pharmaceutical helper molecules) [30]. 

Pharmaceutical excipients. Pharmaceutical excipients in powders mixed with an active ingredient are often compacted into tablets as the final dosage form (Jivraj et al., 2000 Kotte and Rudnic, 1995 Rubinstein, 2000), and these tablets should have adequate mechanical... 

Kibbe, A. H. (2000), Handbook of Pharmaceutical Excipients, Pharmaceutical, London. 

Michaud J, Haest G. Erythritol a new multipurpose excipient. Pharmaceut Technol Em 2003 15(10) 69-72. 

PRODUCTION All operations involved in the preparation of an excipient pharmaceutical product, from receipt of raw materials through the completion of a finished product... 

Rowe, R. Sheskey, P. Weller, P. Handbook ot Pharmaceutical Excipients-, Pharmaceutical Press London, UK, 2003. 

Kibbe H, Handbook of pharmaceutical excipients. Pharmaceutical Press, London, 2000. 

Ilium, L. 1998. Chitosan and its use as a pharmaceutical excipient. Pharmaceutical Research 15 1326-1331. 

Molecules from the Generally Regarded As Safe GRAS list http // www.cfsan.fda.gov. Code of Federal Regulations Title 21 - Food and Drugs, http //www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm, R. C. Rave, P. J. Sheskey and M. E. Quinn, pharmaceutical excipients, in Handbook of Pharmaceutical Excipients, Pharmaceutical Press, New York, 2009. 

J.C. Hooton, Carboxymethyl cellulose Sodium, in R.C. Rowe, P.J. Sheskey (Eds.), Handbook of Pharmaceutical Excipients, Pharmaceutical Press, London, pp.118-121, 2009. 

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