Euodia

Tonga. Infusion of fresh kernel of coconut and Euodia hortensis are taken orally to treat retention of blood clots in the uterus after childbirth (locally called toka-ala ). A mixture of Cocos nucifera, Glochidion concolor, Vigna marina, Morinda citrifolia, Euodia hortensis, and Premna taitensis with lemon juice is taken orally by pregnant... 

These compounds are almost exclusively accumulated in aerial parts and leaves from genera of the Rutaceae such as Bosistoa, Boronia, and Melicope, and rarely in Euodia and Zanthox-ylum. There is a strong tendency towards prenylation at the 7-OH or 4 -OH group. From aerial parts of Boronia coerulescens, a derivative with 3,4 -(9-prenylation was also described (compound 130, Table 12.4). Similarly, only one C-6-(9-derivative was reported from the aerial parts of Melicope. Two 7-epoxy derivatives have already been listed in the previous survey. Combination with methylenedioxy substitution is less frequent, concerning a few sources of Rutaceae and Asteraceae only. Probably, these constituents are partly accumulated externally. 

Simonsen, H.T. et al., Methylenedioxy- and methoxyflavones from Melicope coodeana syn. Euodia simplex. Phytochemistry, 60, 817, 2002. 

Likhiwitayawuid, K., Jongbunprasert, V., and Chanmahasathien, W., Flavones from Euodia... 

Evodia (= Euodia) is considered by some authors to be Melicope + Telradium. 

Aconitum napiforme (Ranunculaceae) kjp 29,129 98 Annona reticulata (Annonaceae) tl 28,1251 87 Annona squamosa (Annonaceae) jnp 44,53 81 Asiasarum heterotropoides (Aristolochiaceae) cpb 26,2284 78 Asiasarum sieboldii (Aristolochiaceae) cpj 44, 211 92 Euodia rutaecarpa (Rutaceae) book 1 Gnetum parvifolium (Gnetaceae) jnp 62,1025 99 Neiumbo nucifera (Nymphaeaceae) cpb 18,2564 70... 

Euodia trichotoma (Rutaceae) pm 59,290 93 Lindera oldhamii (Lauraceae) jnp 49,726 86 Litsea cubeba (Lauraceae) het 9,903 78... 

Euodia xanthoxybides, Fagara leprimrii, Glycosmis arborea,... 

VC Chung, Alkaloids of some Malaysian Euodia Species, M. Sc. Thesis, University of Malaya, Kuala Lumpur, 1989. 

Ouinoline/lsoQuinoline Emetine (45), Psychotrine (46), Buchapine (47) Cephalis ipecacuanha Haplophylum tuberculatum Euodia oxburghiana HSV HIV-RT HIV-RT Cytotoxic/Prote in synthesis HIV-RT HIV-RT [16, 29, 40]... 

A group of yellow, weakly-basic alkaloids derived from acridine. A. occur exclusively in the Ru-taceae (in bark, wood, leaves, roots e. g., Euodia xan-thoxyloides) especially in more than 20 species of the subfamilies Rutoideae, Toddalioideae, and Aurantioi-deae. Most of the naturally occurring A. (>100) are methylated at N and cany oxygen functions at posi-... 

This approach though also has some complications, particularly when the alkaloid has more than one nitrogen and more than one biosynthetic amino acid precursor unit. For example, evodiamine and rutaecarpine, from the fruits of Euodia mtaecarpa (Rutaceae), can be classified as alkaloids derived from tryptophan. In addition, one of the nitrogen atoms of each alkaloid is derived from an anthranihc acid unit. Therefore, these alkaloids can be classified as alkaloids derived fiom tryptophan and as alkaloids derived from anthranilic acid. In this volume, these alkaloids are discussed in Chapter 2.19 as alkaloids derived from tryptophan. 

Euodia rutaecarpa (Rutaceae) is a deciduous tree that grows wild in China and is dioecious.The tree was introduced into Japan around 1720 (Edo era), and is cultivated in various locations in Japan. The dried fruit of this tree is known as Go-shuyu in the Japanese crude drug market, and are used to maintain the health of the stomach, to stimulate the appetite, and to treat stomachache, headache, and vomiting caused by an excess of water in the body. It appears that currently the crude drug that is imported from China is derived from E. officinalis instead of E. rutaecarpa. 

Feeding experiments with [3- C]tryptophan, [ Clfor-mate, [ CH3]methionine, and pHjanthranilic acid in the plant Tetradium Euodia) rutaecarpa, indicated that all labels were incorporated into rutaecarpine (11) and evodia-mine (12). The Ci unit of methionine or formate was incorporated into the 13 position of both alkaloids and into the V-methyl group of evodiamine (Bergman, 1983 Cordell, 1981). 

The dried fruits of Tetradium (Euodia) rutaecarpa have long been used in Chinese medicine for the treatment of headaches, abdominal pain, dysentery, postpartum hemorrhage, and amenorrhea (Bergman, 1983). The alkaloids from these fruits have marked uterotonic effects (King et al., 1980). 

Representatives of this group of alkaloids are widespread in the Rutaceae, especially in the genera Acronycia, Atalan-tia, Balfourodendron, Citrus, Euodia (which should be used... 

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