EU Risk Assessment and Classification under REACH

4-DCB underwent a risk assessment in the European Union which was published in 2004 [57], As a substance produced or imported into the European Union at 10,000-100,000 tonnes per annum, 1,4-DCB was also notified under REACH with a full suite of data in 2009 and the hazards characterized under the regulation on Classification, Labelling, and Packaging of substances and mixtures (CLP). These efforts assembled vastly more data on the ecotoxicity and mammalian toxicity of 1,4-DCB than were available to the US EPA in 1975. 

This characterization of hazards differed markedly from the US EPA s 1975 precis, which did not discuss carcinogenicity and reflected limited aquatic toxicity data. Regulators working under REACH had a far different technical basis for decision making than had the US EPA in the early days of TSCA. 

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