Ethylene glycol dimethacrylate EDMA

The CSPs prepared by the molecular imprint technique have also been used for chiral resolution by CEC [98-100]. Lin et al. [91] synthesized L-aromatic amino acid-imprinted polymers using azobisnitriles with either photoinitiators or thermal initiators at temperatures ranging from 4°C to 60° C. Methacrylic acid (MAA) was used as the functional monomer and ethylene glycol dimethacrylate (EDMA) was used as the cross-linker. The resulting polymers were ground and sieved to a particle size less than 10 pm, filled into the capillary columns, and used for enantiomeric separations of some amino acids at different temperatures. The relationships of separation factor and column temperatures were demonstrated to be linear between the logarithm of the separation factors and the inverse of the absolute temperature (Fig. 24). The authors also compared the obtained chiral resolution with the chiral resolution achieved by HPLC and reported the best resolution on CEC. The chromatograms of the chiral resolution of dl-... 

Chiral polymer-supported thiiranes 401 were prepared by free radical copolymerization of TMA ((3)-thiiranylmethyl-methacrylate) and ethylene glycol dimethacrylate (EDMA) (Equation 60) <2006TA1944>. These chiral thiiranes were transformed into polymer-supported aminothiols by the facile ring opening of the thiirane group with benzylamine and methylamine. These derivatives, complexed with [RuCl2(p-cymene)]2, were used in assymmetric reduction of acetophenone to gave (A)-l-phenylethanol (39% ee from methylamine and 50% ee from benzylamine derivatives). 

Transfer to monomer This type of transfer involves abstraction of hydrogen radicals from the monomer and is negligible in the copolymerisation of MMA and ethylene glycol dimethacrylate (EDMA) [15]. 

In a subsequent study, the Co coordinated assembly was grafted onto a cross-linked poly(glycidoxypropylmethacrylate) (GMA)-ethylene glycol dimethacrylate (EDMA) support surface. The template and Co ions were then leached out from the matrix. This surface grafted polymer exhibited turnover, Michaelis-Menten kinetics and mechanisms such as inhibition by tosyl phenyl alanyl chloromethyl ketone and inhibition on acetylation of hydroxyl group of 2-hydroxyethylmethacry-late (HEMA), similar to native chymotrypsin. 

Most of the imprinted sorbents used in MISPE were prepared using MAA and ethylene glycol dimethacrylate (EDMA) as monomers. In these cases elution of more weakly bound analytes such as triazines [19,30,32], 7-hydroxy-coumarin (2) [26] or theophylline (12) [28] can be achieved using methanol or water as elution solvent. For more strongly bound analytes such as stronger nitrogen Bronsted bases, efficient elution has been achieved using eluents of the same base solvent but with the addition of small amounts of acids (e.g. acetic acid, trifluoroacetic acid (TEA)) or base (e.g. triethylamine (TEA)) [20-22,25,33]. 

Quartz crystal microbalance (QCM) Surface plasmon resonance (SPR) Piezoelectric quartz crystal (PQC) Bulk acoustic wave (BAW) surface acoustic wave (SAW) 4-vinylpyridine (4-VP) Ethylene glycol dimethacrylate (EDMA) Methacrylic acid (MAA), Ethylene glycol dimethacrylate (EDMA) IV-phenylacrylamide (PAM) Diethylamino ethyl methacrylate (DEAEM). 

Ethylene glycol dimethacrylate (EDMA)-methacrylic acid (MAA) copolymer-based imprinted polymer particles were mixed with poly(vinyl chloride) in THF, and the solution was then spread on the electrode of the QCM by spin coating. After evaporation of the THF, the polymer particles were immobilized on the surface. A phenobarbital-imprinted QCM sensor prepared in this way worked in ethanol [1], while epinephrine- and caffeine-imprinted QCMs worked in buffer solutions (pH 6.0 and pH 8.0, respectively) [2, 3],... 

Eldred [1974] electron-irradiated EPR and EPDM in air, in the presence or absence of the following crosslinking agents ethylene glycol dimethacrylate, EDMA, 1,4-hexadiene, HD,... 

Ethylene glycol dimethacrylate (EDMA) Photoreactor (e.g., Lamag UV-lamp) 4°C cold-room (optional)... 

The fact that a large number of templates has been successfully imprinted using basic recipes has led to the proliferation of MIPs of relatively low complexity, most of which have been based on a restricted number of synthetic trials (even though in some cases supported by spectroscopic or computational hints). The majority of basic templates have been imprinted using methacrylic acid (MAA) as monomer (seeTable 5.6A in Ref. 1), the acidic ones using vinylpyridines (VPY) (seeTable 5.6B in Ref 1). Ethylene glycol dimethacrylate (EDMA) is the most used crosslinker (see Table 2.5 in Ref 1), acetonitrile, dichloromethane, chloroform, toluene the most used solvents. 

Traditional noncovalent MIPs employ functional monomers such as methacrylic acid (MAA) or 4-vinylpyridine (4-Vpy) and cross-linking monomers such as divinyl benzene (DVB), ethylene glycol dimethacrylate (EDMA), or trimethylolpropane... 

A fluorescent sensor for dansyl-phenylalanine (dansyl-Phe-OFl) (Fig. 2, 1) has been successfully constructed by using methacrylic acid (MAA) and 2-vinyl-pyridine (2VPy) as the functional monomers and ethylene glycol dimethacrylate (EDMA) as the cross-linker. The fluorescence of the imprinted polymers upon analyte binding was detected using fiber optics, and the signal was found to be a function of the analyte concentration. The sensor also showed a moderate degree... 

MMA), when copol3rmerised with ethylene glycol dimethacrylate (EDMA) or polyethylene fumarate (PEF), but not with styrene, enters stage II sharply at the gel point. A plausible model proposed by Gordon and Roe leads to a parameter-free rate equation fig. M-), which fits extensive measurements on MMA/EDMA and MMA/PEF very well over the range 0 < < 6 Fig. M- contains... 

EPDMs are more suitable than EPMs for high energy radiation crosslinking. A determining factor in keeping costs down is the use of activators,of which trimethylpropane trimethacrylate (TMPT) and ethylene glycol dimethacrylate (EDMA) have been found the most efficient. 

The composition of the polymerization mixture was as follows L- or D-Phe-An [43], as print molecule (1.956 mmol) MAA, as functional monomer (7.86 mmol) ethylene glycol dimethacrylate (EDMA), as cross-linker (39.3 mmol) 2,2 -azobis(2-methylpropionitrile) (AIBN), as initiator (0.57 mmol) acetonitrile, as solvent (12 ml). The MAA/print molecule ratio was 4 1. 

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