Ethylbenzene, partition coefficient

Partition coefficients of ethylbenzene for other media (water/air, blood/air, oil/air, oil/water and oil/blood) have also been measured (Sato Nakajima, 1979)... 

Overview. The capillary column IGC technique was used to determine the partition coefficients and diffusion coefficients of a number of solvents (methanol, acetone, methyl acetate, ethyl acetate, propyl acetate, benzene, toluene, and ethylbenzene) in poly(methyl methacrylate). Measurements below the glass transition temperature were obtained for the PMMA/methanol system. 

Although broad observations on the different partitioning behaviour of compotmds such as naphthalene and glucose have been made since the later years of the nineteenth century, it was only in the 1960s that careful quantitative measurements allowed more confident predictions of partition coefficients to be made for compounds for which they were previously unknown. Log P for benzene between octanol and water (the most commonly quoted solvent pair, as described above) is 2.13. The value for toluene (methylbenzene) is 2.79, so the extra -CH2-contributes 0.66. The value of log P for ethylbenzene is 3.45, so the extra -CH2- again contributes 0.66. With some provisos, it is found that the contribution of a specific molecular fragment to log P is more or less constant. This is discussed in more detail in Chapter 9. 

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