Ethyl p-Methoxybenzoate

The simplest possible use that can be made of the Hammett equation is to calculate k or K for a specific reaction of a specific compound, where this information is not available in the literature, or indeed where the actual compound has not even been prepared yet. Thus it is known that the base-catalysed hydrolysis of ethyl m -nitrobenzoate is 63-5 times as fast as the hydrolysis of the corresponding unsubstituted ester under parallel conditions what then will be the comparable rate for base-catalysed hydrolysis of ethyl p-methoxybenzoate under the same conditions Looking at the table of [Pg.374]

ETHYL METHANESULFONATE see EMF500 ETHYL METHANESULPHONATE see EMF500 ETHYL METHANOATE see EKLOOO ETHYL METHANSULFONATE see EMF500 ETHYL METHANSULPHONATE see EMF500 ETHYL-4-METHOXYBENZOATE see AOVOOO ETHYL-p-METHOXYBENZOATE see AOVOOO ETHYL-2-METHYLACRYLATE see EMFOOO... 

Synonyms p-Anisic acid ethyl ester Ethyl anisate Ethyl-4-methoxybenzoate Ethyl-p-methoxybenzoate... 

Ethyl methane carboxamide (INCI). See N-Ethyl-p-menthane-3-carboxamide Ethyl methanoate. See Ethyl formate Ethyl 2-methoxybenzoate. See Ethyl o-anisate, Ethyl-4-methoxybenzoate. See Ethyl-p-anisate Ethyl o-methoxybenzoate. See Ethyl o-anisate Ethyl-p-methoxybenzoate. See Ethyl-p-anisate Ethyl 2-methoxybenzyl ether CAS 64988-06-3 EINECS/ELINCS 265-301-3 Synonyms o-(Ethoxymethyl) anisole Empirical C10H14O2 Properties M.w. 166.22 Uses Fragrance in cosmetics... 

Kindler [Twi., 450( 1), 1926] has studied the alkaline hydrolysis of the ethyl esters of a number of substituted benzoic acids. The m-nitro compound was found to have a rate constant 63.5 times as fast as the unsubstituted compound. What relative rate constant is predicted for the reaction of p-methoxybenzoate by the Hammett equation The value based on experimental results is 0.214. 

Aconine, the amino alcohol, is the parent of two ester-alkaloids, aconitine (the acetate benzoate) and jesaconitine (the acetate p-methoxybenzo-ate), and differs from mesaconine, the parent of mesaconitine (the acetate benzoate), only in the A-alkyl substituent. Aconine carries an 7V-ethyl (40, 49) and mesaconine an A-methyl group these two compounds thus yield the same nitro-AT-nitroso derivative, and aconitine and mesaconitine give the same oxidation product, oxonitine (41), with elimination of the A-alkyl group. It is convenient, therefore, to combine the discussion of these closely related alkaloids. 

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