Ethyl n-propylacetoacetate

Thus if R = n-propyl (ethyl n-propylacetoacetate), methyl n-butyl ketone is produced. The preparation of this ketone is described in Section 111,152 under Ethyl Aceioacetate. 

Cool the mixture and decant the solution from the sodium bromide wash the salt with two 20 ml. portions of absolute alcohol and add the washings to the main solution. Distil off the alcohol, which contains the slight excess of n-propyl bromide used in the condensation, through a short fractionating column from a water bath. The residue A) of crude ethyl n-propylacetoacetate may be used directly in the preparation of methyl n-butyl ketone. If the fairly pure ester is required, distil the crude product under diminished pressure and collect the fraction boihng at 109-113727 mm. (183 g.) (R). 

To prepare methyl n-butyl ketone, add the crude ester (A) or the redistilled ethyl n-propylacetoacetate B) to 1500 ml. of a 5 per cent solution of sodium hydroxide contained in a 4-litre flask equipped with a mechanical stirrer. Continue the stirring at room temperature for... 

Ethyl phenylmalonate, 1003 Ethylphenylnitrosamine, 570 Ethyl phenyloxalacetate, 1003,1004 Ethyl n-propylacetoacetate, 475, 481 Ethyl propane-1 1 2 3-tetracarboxy-late, 912, 913... 

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