Ethyl dimethylaminophosphoric acid

FIGURE 52.1. Metabolic detoxification of warfare nerve agents tabun, sarin, soman, and VX in mammals in vivo. Chemical names of metabolites are EDMPA - ethyl dimethylaminophosphoric acid, IMPA - isopropyl methylphosphonic acid, PMPA - pinacolyl methyl-phosphonic acid, EMPA - ethyl methylphosphonic acid, and MPA - methylphosphonic acid. 

FIGURE 59.1 Metabolic detoxification of tabun, soman, sarin, cyclosarin, and VX. Abbreviations EDMPA, ethyl dimethylaminophosphoric acid EPA, ethyl phosphoric acid EPCA, 0-ethyl-cyanophosphoric acid IMPA, isopropyl methylphosphonic acid PMPA, pinacolyl meth-ylphosphonic acid CHMPA, cyclohexyl methylphosphonic acid EMPA, ethyl methylphosphonic acid MPA, methylphosphonic acid DAET, 2-(diisopropylamino) ethanethiol DAEMS, 2-(diisopropylaminoethyl) methylsulphide TMT, thiol S-methyltransferase (EC 2.1.1.9) (Nakajima et al., 1998 Katagi et al., 1999 Jokanovic, 2001, 2009 Evans et al., 2008 Black, 2010 Tenberken et al., 2010 Reiter et al., 2011 Black and Read, 2013 Kranawetvogl et al., 2013). 

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