Ethyl, amine sulphate

On the other hand, Elliott and his co-workers 4 maintain that the evidence for the nitro- structure is unsatisfactory, and that the p-nitro-dimethylaniline produced with dimethylaniline is a secondary product obtained either by oxidation of the nitroso-compound or by direct nitration of the amine. The addition of ethyl hydrogen sulphate to a solution of nitrosulphonic acid in sulphuric acid does not yield nitro -ethane. Elliott suggests that the crystalline acid is essentially the nitroso- form, ON. O. SO 2. OH, but that in the molten condition and in sulphuric acid solution this form is in equilibrium with another of yO ... 

To a solution of 0.5 g of the amine in 4 ml of dry pyridine and 10 ml of dry benzene (CAUTION), add dropwise 0.5 ml of benzoyl chloride. Heat the mixture under reflux on a water bath at 60- 70 °C for 20-30 minutes and then pour into 80-100 ml of water. Separate the benzene layer and extract the aqueous layer with 10 ml of benzene. Wash the combined benzene solutions with 5 ml of 5 per cent sodium carbonate solution, followed by 5 ml of water, and dry with magnesium sulphate. Filter off the desiccant through a small fluted filter paper and concentrate the benzene solution to a small volume (3-4 ml). Stir 15-20 ml of hexane into the residue the crystalline product separates. Filter and wash with a little hexane. Recrystallise from a mixture of cyclohexane with hexane or with ethyl acetate alternatively use ethanol or dilute ethanol for recrystallisation. 

Buper-dry ethyl alcohol on a water hath whilst adding 75 g. of sodium introduce more alcohol (about 300 ml.) to maintain a vigorous reaction. When all the sodium has passed into solution, cool, dilute with 250 ml. of water and distil gently until the b.p. reaches 96° add a further 200 ml. of water and repeat the distillation to ensure the complete removal of the alcohol. The amine remains as a layer on the strongly alkaline solution extract it with ether, dry the ethereal solution w ith sodium hydroxide or anhydrous calcium sulphate, remove the ether on a water bath, and distil the residue under diminished pressure. Collect the... 

A cycloheptatrienide trianion would have ten ir-electrons and thus might be a stablised (4n+2) electron system. There is evidence for its formation in solution, when either hepta-1,3,6-triene or, more surprisingly, hepta-1,6-diene is treated with n-butyl lithium in tetramethylethylenediamine [390]. The lithium salt is apparently solvated by the amine. Its and n.m.r. spectra show singlets at 6 4.55 and 66.0, respectively. It reacts with deuterium oxide to give a mixture of trideuteriocycloheptadienes and with ethyl sulphate to give a mixture of triethylcycloheptadienes. 

For heterocyclic bases a method of determination was proposed based on quaternisation with ethyl iodide or methyl sulphate, followed by treatment with basic potassium permanganate, ydatile amines are thus formed which can be collected in standardised mineral acid arid back titrated... 

To a mixture of aldehyde (2 1 mmol), secondary amine (3 1 mmol) and indole (1 1 mmol) was added with L-proline (30 mol %) in a 25 mL round-bottom flask, and the reaction mixture was stirred at room temperature till the completion of the reaction (5-18 h monitored by TLC). After completiOTi, the reaction mixture was diluted with water and extracted with ethyl acetate, dried over sodium sulphate and evaporated in vacuo to give crude product, which was purified by silica gel (230-400 mesh) colunm chromatography to afford the corresponding 3-amnio alkylated indole derivative 4 with good yield (68-87%). The products were characterized oti the basis of spectral and elemental analyses. 

Chem. Descrip. N-alkyl coco demethyl ethyl ammonium ethyl sulphate, butyl alcohol (< 5%), coco alkyidinethyl amines (< 5%)... 

Ethylene sulphate underwent ring opening with nucleophiles such as amines, mercaptides, acetylides, and alkyl-lithiums to give 3- ubstituted ethyl sulphates. ... 

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