3-Ethoxycarbonyl-2-phenyl

The electrophilic properties of substituted 6//-l,3-thiazine-6-ones (208) in solution also shows reactivity at C-2 in acidic conditions and at C-6 in basic conditions. The regioselective reaction of 4-ethoxycarbonyl-2-phenyl-6//-l,3-thiazine-6-one with dimethylamine leads, after ring opening and reclosure, to two diasteriomeric 5-dimethylcarboxamido-4-ethoxy-carbonyl-2-phenyl-A2-thiazolines 209 and 210, whose structures were confirmed by X-ray diffraction studies on 210 (Scheme 84) (88BSF897). Com-... 

Carbon dioxide is lost on thermolysis of 4-ethoxycarbonyl-2-phenyl-A2-l,3,4-oxadiazo-line-5-thione. Migration of the ethyl group from oxygen to sulfur leads to the product, 5-ethylthio-2-phenyl-l,3,4-oxadiazole (78IJC(B)146). 

These in situ generated unstable vinyllead triacetates react with soft carbon nucleophiles to give moderate to good yields of C-vinylated products. This method is potentially very useful in organic synthesis. As an example, styryllead triacetates reacted with 4-ethoxycarbonyl-2-phenyl-4,5-dihydrooxazol-5-one (64, R=Ph) to afford, after hydrolysis, the a-styryl-V-benzoylaminoesters in relatively modest yields.82 Better yields were obtained with the 2-mcthyM,5-dihydrooxazol-5-one analog (64, R = Me) (Equation (60)).83... 

Durch Einwirkung von waBriger Kaliumhydroxid-Losung auf 4-[Ethoxycarbonyl-(2-phenyl-hydrazono)-methyl]-l, 3-dinitro-benzol (R = OC2H5) tritt Cyclisierung unter Abspaltung der Nitro-Gruppe zu 3-Carboxy-6-nitro-1 -phenyl-1 H-indazol (R = OH)176, l7X- 57°-571 ein. 

COOC2H5 /Nicl2 170- 180 (2-Ethoxycarbonyl-phenyl)- methyl-phosphirtsaure-ethyl- ester 78 148-150 0,6 (0,08) 521... 

Triazen l-(4-Ethoxycarbonyl-phenyl)-3-hydroxymethy 1-3-methyl- E16a, 1203 (Ar — Nf + Amin)... 

Tellurau Butyl-(2-ethoxycarbonyl-phenyl)- E12b, 452 (CO-Cl - COOR)... 

Alkyl phenyl telluriums and diaryl telluriums react with Grignard reagents in THF or diethyl ether in the presence of catalytic amounts of nickel- or cobalt-phosphane complexes. Tellurium is precipitated. The organic groups combine to form in most cases all three possible coupling products in ratios determined by reaction conditions . The reaction of ( Z,)-phenylethenyl phenyl tellurium and phenyl magnesium bromide formed almost exclusively ( Zj-stilbene in quantitative yield. ( ZJ-Ethoxycarbonylethenyl phenyl tellurium and phenyl magnesium bromide reacted differently ( Fj-ethoxycarbonyl-(phenyl)-ethene and diphenyl tellurium were produced. Tellurium was not formed. ... 

Xanthylium, 9-[2-(ethoxycarbonyl)phenyl]-3,6-bis(elhyl-amino)-2,7-dimethyl-, chloride. 

To a 0.9 mL THF solution containing 4.3 mg Pd(OAc)2 (0.02 mmol, 10 mol %), tri-2-furylphosphine (5.1 mg, 0.02 mmol, 10 mol %), 32.7 mg triethylamine (0.32 mmol), and 75.2 mg 4-iodobenzoic acid ethyl ester (0.27 mmol), was added 65.7 mg (2-pyridyl)-l-hexenyl-dimethylsilane (0.30 mmol) under argon the reaction mixture was stirred at 60°C for 3 h. After the mixture was cooled to room temperature, 48.2 mg 4-iodoacetophenone (0.20 mmol) and 0.46 mL 1 M TBAF solution in THF were added to the reaction mixture, and this reaction mixture was stirred at 60°C for 14 h. The catalyst was removed by filtration through a short silica gel pad (EtOAc). The filtrate was evaporated, and the residue was chromatographed on silica gel (hexane/EtOAc, 10/1) to afford 48.6 mg ( )-l-(4-acetyl)phenyl-2-(4-ethoxycarbonyl)phenyl-l-hexene as a colorless oil, in a yield of71%. 

CAS 989-38-8 EINECS/ELINCS 213-584-9 Synonyms Basic red 1, monohydrochloride Basic rhodamine yellow Basic rhodaminic yellow Benzoic acid, o-(6-(ethylamino)-3-(ethylimino)-2,7-dimethyl-3H-xanthen-9-yl)-, ethyl ester, monohydrochloride Cl 45160 Ethyl o-(6-(ethylam i no)-3-(ethyl i m i no)-2,7-dimethyl-3H-xanthen-9-yl) benzoate monohydrochloride Rhodamine 6G Xanthylium, 9-(2-(ethoxycarbonyl) phenyl)-3,6-bis (ethylamino)-2,7-dimethyl-, chloride Classification Azobenzene Empirical C28H31CIN2O3 Formula C28H30N2O3 CIH Properties Bluish-pink cryst. or red-brn. solid sol. (mg/ml) > 100 mg in 95% ethanol (19.5 C), < 1 mg in water, DMSO, acetone (20 C) m.w. 479.02 volatilizes 200 C... 

Ethoxycarbonyl) phenyl-3,6-bis (ethylamino)-2,7-dimethylxanthylium molybdatetungstatephosphate. See Pigment red 81... 

A -[6-Amino-9-[2-(ethoxycarbonyl)phenyl]-7-methyl-3//-xanthen-3-ylidene]-A-ethylethanaminium(l 4-), see R-00004 (2-Aminoethoxy)diphenoxyborane, A-00172 4-Amino-4 -ethoxydiphenylamine, in A-00185 (2-Aminoethoxy)diphenylborane, A-00173... 

The high reactivity of the exocyclic 4-NH- group is again illustrated by the reaction of 2-imino-3-phenyl-4-amino-5-(ethoxycarbonyl)-4-thiazoline with EtOjCCH SCN, which yields 134 (296), and by the intramolecular preparation of the dihydrothiazolo[4,5-h]pyridine derivative 136 (297) (Scheme 89). 

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