Ethanol hydrolysis

The furan (450) is also formed on photolysis of 1,3-diphenylindenone epoxide (449) in ethanol. Hydrolysis of the epoxide (449) in acetic acid with hydrogen chloride was also... 

American workers needed to prepare the bis-amino acid 1 and adopted a literature procedure in which two equivalents of diethyl acetamidomalonate were to be alkylated with one equivalent of l,4-dichloro-2-butyne using two equivalents of sodium ethoxide in hot ethanol. Hydrolysis and decarboxylation of the dialkylated malonate would then give 1. This alkylation reaction was carried out, but ten equivalents of sodium ethoxide were used rather than two. This resulted in formation of ethyl 5-methylpyrrole-2-carboxylate in ca. 40% yield. Further study showed that the reaction to produce the pyrrole required equimolar amounts of the acetamidomalonate and the dichlorobutyne, excess of sodium ethoxide, and heating. No pyrrole was formed at room temperature. 

PcrfIuoroHlkyl)ethanols Hydrolysis of Iodides General Procedure ... 

The azide-alkyne click reactions are useful to attach a number of polar FGs including various azobenzene moieties to the pendants of poly(l-phenyl-5-chloro-l-pentyne), (Eq. (7)) [90]. Nucleophilic substitutions of the same starting polymer result in the formation of an imidazole-functionalized, disubstituted acetylene polymer, (Eq. (8)) [91]. The degree of incorporation of the imidazole moiety is about 65%, and the product polymer exhibits good solubility in ethanol. Hydrolysis reaction of poly[l-(/w-methoxycarbonylphenyl)-l-octyne] yields a carboxy-functionalized disubstituted acetylene polymer poly[l-(/w-carboxyphenyl)-l-octyne], (Eq. 9) [92]. Hydrazine-catalyzed deprotection of poly[l-phenyl-ll-Af-benzimide-l-undecyne] affords the corresponding polyamine, which can be further ionized with hydrobromic acid to give a polyelectrolyte ammonium salt, (Eq. (10)) [93]. 

SE reflux 2 h with 80% aqueous ethanol hydrolysis with 3-glucosidase SE ethanol SPE Polystyrene resin (NKAO) eluted with 20% ethanol SE 80% aqueous methanol hydrolysis ceUulase in 0.1 M acetate buffer pH 5.0 LLE ethyl acetate... 

Alcohols Methanol, ti-bu-tanol, ethanol Hydrolysis of dialkylsulfates... 

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