Estrogens susceptibility factors

Considerable information, although not entirely consistent, is available on predisposing factors (SED-11, 108) (245,269,283). The condition is apparently more common in women and the elderly and elderly women in particular seem susceptible to a relatively severe form of the condition (SED-11,108) (269,284). It has been suggested that estrogen plays a role (285,286). Here too, however, the epidemiology has been challenged not all studies have confirmed that women are more vulnerable (287), although the consensus supports this conclusion. 

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