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Esterase aliesterases

Pond, A.L., Chambers, H.W., Chambers, J.E. (1995). Qrgano-phosphate detoxication potential of various rat tissues via A-esterase and aliesterase activities. Toxicol. Lett. 70 245-52. [Pg.1030]

Detoxification of organophosphorus pesticides before they can reach their target sites is probably the main reason for poor correlation between carcinogenicity and electrophilicity/mutagenicity. The problem is further complicated by the fact that several different enzymes are involved in the metabolic detoxification of organophosphorus pesticides. For example, paraoxon, tetrachlojTvinphos and dimethoate are preferentially detoxified by A-esterase (paraoxonase), GSH-dependent S-alkyltransferase and carboxyesterase (aliesterase), respectively whereas chlorfenvinphos is mainly detoxified by NADPH-dependent oxidative dealkylation... [Pg.192]

Chambers JE, Chambers HW (1990) Time course of inhibition of acetylcholine esterase and aliesterases following parathion and paraoxon exposures in rats. Toxicol Appl Pharmacol 103 420-429... [Pg.251]

See other pages where Esterase aliesterases is mentioned: [Pg.167]    [Pg.167]    [Pg.86]    [Pg.49]    [Pg.31]    [Pg.37]    [Pg.67]    [Pg.67]    [Pg.213]    [Pg.46]    [Pg.57]    [Pg.69]    [Pg.158]    [Pg.804]    [Pg.1039]    [Pg.1894]    [Pg.259]    [Pg.173]    [Pg.62]    [Pg.825]    [Pg.889]   
See also in sourсe #XX -- [ Pg.86 ]



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