Plasmodium essential oils against

Table I. The Main Chemical Constituents and Antiplasmodial Activity of Twenty Essential oils Against Plasmodium falciparum FCM29 strain...

An aqueous ethanolic (50%) extract of fresh leaves of H. coronarium from Brazil showed hypotensive [209] and diuretic [216] activities in rat. Leaf essential oil ofH. coronarium had anti-bacterial activity [217]. Stems ofH. coronarium were reported to possess anti-cercarial activity [218]. An ethanolic extract of the stems of H, coronarium showed anti-malarial activity against Plasmodium falciparum and also possessed cytotoxic activity [211]. Petroleum ether extract of the dried entire plants of H. 

Essential oils have also been examined for their direct effect, both in vitro and in vivo, against Herpetomonas, Leishmania, Plasmodium, and Trypanosoma species. Recent examples are given in Table 13.3. Unfortunately, the promising results have not encouraged human clinical trials as yet. 

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