Escherichia coli enzyme induction

Inductest Escherichia coli A-lysogen Phage or enzyme induction <3 wk L L M NA... 

Trent, M.S., Ribeiro, A.A., Lin, S., Cotter, R.J., Raetz, C.R.H. An inner membrane enzyme in Salmonella typhimurium and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A Induction in polymyxin resistant mutants and role of a novel lipid-linked donor. J Biol Chem 276 (2001b) 43122-43131. 

GH 2. The tetrameric lacZ (3-galactosidase of Escherichia coli has been intensively investigated for over 40 years, initially because of its relationship to Monod s classic work on enzyme induction. A very large set of data accumulated by Wallenfels and Weil unfortunately had to be discarded because it was obtained in inhibitory Tris buffers.The first glycosyl-glycosidase intermediate to become kinetically accessible was with this en-zyme the 2-fluoro-2-deoxy-a-D-galactopyranosyl enzyme, the parent enzyme and ES complexes have since been crystallised and its structure determined. 

The first demonstrated example of enzyme induction came from studies conducted in the 1950s on the bacterium Escherichia coli. p-galactosidase, an enzyme required for the utilization of lactose, catalyzes the hydrolysis of lactose to D-galactose and o-glucose. 

Bacteria Escherichia coli Release of glucose inhibition of enzyme induction (see Catabolite repression). Initiation of mRNA synthesis mediated by a specific cAMP receptor protein (catabolite gene activator protein). Inhibition of the degradation of mRNA bound to ribosomes. Stimulation of the synthesis of many enzymes... 

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