Escherichia coli central carbon metabolism

Sauer, U., Lasko, D. R., Fiaux, J., Hochuli, M., Glaser, R., Szyperski, T., Wuthrich, K., and Bailey, J. E. (1999). Metabolic flux ratio analysis of genetic and environmental modulations of Escherichia coli central carbon metabolism. J. Bacteriol, 181(21), 6679-6688. 

This is not the place to expose in detail the problems and the solutions already obtained in studying biochemical reaction networks. However, because of the importance of this problem and the great recent interest in understanding metabolic networks, we hope to throw a little light on this area. Figure 10.3-23 shows a model for the metabolic pathways involved in the central carbon metabolism of Escherichia coli through glycolysis and the pentose phosphate pathway [22]. 

C. Chassagnole, N. Noisommit Rizzi, J. W. Schmid, K. Mauch, and M. Reuss, Dynamic modeling of the central carbon metabolism of Escherichia coli. Biotechnol. Bioeng. 79(1), 53 73 (2002). 

Fig. 13.1 Central carbon metabolism of Escherichia coli. See Section 13.2 for details.

Fischer, E. Sauer, U. Metabohc flux profihng of Escherichia coli mutants in central carbon metabolism using GC-MS. Eur. J. Biochem. 2003, 270, 880-891. 

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