Escherichia coli asparaginase from

E. Harms, A. Wehner, M. P. Jennings, et al. Construction and expression systems for Escherichia coli asparaginase II and two-step purification of the recombinant enzyme from periplasmic extracts. Protein Exp. Purif. 2 144 (1991). 

Pegylated-L-asparaginase, PEG-conjugated L-asparaginase (of Escherichia coli) Erwinia L-asparginase is extracted from Erwinia chrysanthemi. 

Asparaginases with antilymphoma activity have also been found in extracts of Serratia marcescens (35-37), Erwinia carotovora (38), and Proteus vulgaris (36). Escherichia coli extracts contain a second asparaginase that is devoid of antilymphoma activity (39), and a similarly inactive enzyme has been found in a fungus, Fusarium tricinctum (40). An enzyme from Streptomyces griseus has L-asparaginase activity when assayed in tris-Cl (pH 8.6) but little or no activity in sodium borate (pH... 

T. Yosiumoto, H. Nishimun, Y.Saito.etal. Characterization of polyethylene glycol-modified 1-asparaginase from Escherichia coli and its application to therapy of lEUksnhJpn. J. Cancer Ret. 77 1264 (1986). 

Colaspase and crisantaspase are the British Approved Names of asparaginase obtained from cultures of Escherichia coli and Erwinia carotovora respectively. 

L. T. Mashbum and J. C. Wriston. Tumor inhibitory effect of 1-asparaginase from Escherichia coli. Arch. Biochem. 705 450 (1964). 

T. Maita and G. Matsuda. The primary structure of 1-asparaginase from Escherichia coli. Hoppe Seyler s Z Physiol. Chem. 367 105 (1980). 

It is a preparation from Escherichia coli containing the enzyme L-asparaginase amidohydrolase. 

The influence of glycosylation on tissue uptake of enzymes has been investigated. Lactose and A-acetylneuraminyl-Iactose have been coupled to Escherichia coli L-asparaginase by reductive amination with sodium cyanoborohydride (see Scheme 2, Vol. 10, Part II, Chapter 8, p. 428). Oligosaccharides obtained from... 

Pedersen, P.B. (2006) Asparaginase, PPV 24743—Test for mutagenic activity with strains Salmonella typhimurium and Escherichia coli. Unpublished report No. 20068039 from Novozymes A/S, Bagsvssrd, Denmark. Submitted to WHO by Novozymes A/S, Bagsv rd, Denmark. 

L-Asparaginase from Escherichia coli catalyzes the conversion of the diazo ketone analog of L-asparagine, diazo-4-oxo-L-norvaline (DONV),... 

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