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Erythropoietin composition

Hematopoiesis is the process of blood cell production that takes place in the bone marrow. Through a complex series of regulatory events, stem cells are differentiated into various types of cells, including red blood cells. Stem cell differentiation is responsive to exogenous stimuli and can be upregulated to resupply a deficient cell population. However, only a limited number of therapeutics (iron, hemin, or erythropoietin, for example) can stimulate Hb-replete red blood cell formation. Recognition of the poor bioavailability of many iron compounds or hemin compositions and the improved safety profile of a tHb relative to rmmodified Hb has renewed the interest in Hb administration as... [Pg.363]

Storring P L, Tiplady R J, Gaines Das R E, et al. (1998). Epoetin alfa and beta differ in their erythropoietin isoform compositions and biological properties. Br. J. Haematol. 100 79-89. [Pg.804]

Pistel KF, Bittner B, Koll H, Winter G, Kissel T. Biodegradable recombinant human erythropoietin loaded microspheres prepared from linear and star-branched block copolymers Influence of encapsulation technique and polymer composition on particle characteristics. J Control Release 1999 59 309-325. [Pg.249]

Rong X, Mo X, Ren T, Yang S, Yuan W, Dong J et al. Nenroprotective effect of erythropoietin-loaded composite microspheres on retinal ganglion cells in rats. European Journal of Pharmaceutical Sciences Official Journal of the European Federation for Pharmaceutical Sciences. July 17,2011 43(4) 334-342. PubMed PMID 21621611. [Pg.1031]

See other pages where Erythropoietin composition is mentioned: [Pg.446]    [Pg.437]    [Pg.68]    [Pg.102]    [Pg.35]    [Pg.2006]    [Pg.654]    [Pg.206]    [Pg.400]    [Pg.341]   
See also in sourсe #XX -- [ Pg.547 ]

See also in sourсe #XX -- [ Pg.340 ]

See also in sourсe #XX -- [ Pg.547 ]



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Erythropoietin

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