Erythrocytes, selective permeability

From c. 1900 experiments, many of them with mammalian erythrocytes, indicated cells were selectively permeable to a range of low molecular weight neutral solutes. If molecules with similar structures were added to the suspension medium, entry of the test solute might be reduced. 

Siemon H, Schneider H, Fuhrmann GF. 1982. Vanadium increases selective K+-permeability in human erythrocytes. Toxicology 22 271-278. 

Elford, B. C., Haynes, J. D., Chulay, J. D., and Wilson, R. J. (1985). Selective stage-specific changes in the permeability to small hydrophilic solutes of human erythrocytes infected with Plasmodium falciparum. Mol. Biochem. Parasitol. 16,43-60. 

Fuhrmann GF, Huttermann J and Knaue PA (1984) The mechanism of vanadium action on selective KT-permeability in human erythrocytes. 

The Mn(ii)-based SOD mimics have numerous potential advantages over the SOD enzymes as potential therapeutic agents, including membrane permeability, selective reactivity for superoxide, immunogenicity effects, stability, and cost. Table 1 compares characteristics of the Mn(ii)-based SOD mimics with R = H versus those of bovine erythrocyte Cu,Zn SOD. 

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